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Cash and Cash Equivalents, Restricted Cash and Investments

9 Months Ended

Sep. 30, 2025

Cash, Cash Equivalents, and Short-Term Investments [Abstract]

Cash and Cash Equivalents, Restricted Cash and Investments

Cash and Cash Equivalents, Restricted Cash and Investments

The fair value of cash and cash equivalents, restricted cash and investments held are as follows:  

						As of September 30, 2025
						Amortized Cost						Gross Unrealized Gains						Gross Unrealized Losses						Estimated Fair Value
						(in thousands)
Cash and cash equivalents						$	49,656					$	—					$	—					$	49,656
Restricted cash						29,000						—						—						29,000
Total cash and cash equivalents and restricted cash						$	78,656					$	—					$	—					$	78,656
Securities maturing within one year:
U.S. treasury securities						43,223						24						—						43,247
Corporate debt securities						23,042						9						(4)						23,047
Total short-term investments						$	66,265					$	33					$	(4)					$	66,294
Total cash and cash equivalents, restricted cash and short-term investments						$	144,921					$	33					$	(4)					$	144,950
						As of December 31, 2024
						Amortized Cost						Gross Unrealized Gains						Gross Unrealized Losses						Estimated Fair Value
												(in thousands)
Cash and cash equivalents						$	66,656					$	—					$	—					$	66,656
Restricted cash						—						—						—						—
Total cash and cash equivalents and restricted cash						$	66,656					$	—					$	—					$	66,656
Securities maturing within one year:
U.S. treasury securities						127,884						106						—						127,990
Corporate debt securities						43,299						30						(18)						43,311
Total short-term investments						$	171,183					$	136					$	(18)					$	171,301
Total cash and cash equivalents, restricted cash and short-term investments						$	237,839					$	136					$	(18)					$	237,957

As of September 30, 2025 and December 31, 2024, Lexicon’s investments in an unrealized loss position had an estimated fair value of $16.3 million and $12.9 million, respectively. There were no realized gains or losses during either of the nine month periods ended September 30, 2025 and 2024.

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- Definition

The entire disclosure for cash and cash equivalent footnotes, which may include the types of deposits and money market instruments, applicable carrying amounts, restricted amounts and compensating balance arrangements. Cash and equivalents include: (1) currency on hand (2) demand deposits with banks or financial institutions (3) other kinds of accounts that have the general characteristics of demand deposits (4) short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates. Generally, only investments maturing within three months from the date of acquisition qualify.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 210
-SubTopic 10
-Name Accounting Standards Codification
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02(1))
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147480566/210-10-S99-1

Reference 2: http://www.xbrl.org/2003/role/disclosureRef
-Topic 944
-SubTopic 210
-Name Accounting Standards Codification
-Section S99
-Paragraph 1
-Subparagraph (SX 210.7-03(a)(2))
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147478777/944-210-S99-1

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- References

No definition available.

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