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Cover
Nov. 06, 2025
Aug. 06, 2025
Cover [Abstract]    
Document Type   8-K
Entity Tax Identification Number   76-0474169
Entity Registrant Name   Lexicon Pharmaceuticals, Inc.
Entity File Number   000-30111
Entity Incorporation, State or Country Code   DE
Entity Address, Address Line One   2445 Technology Forest Blvd., 11th Floor
Entity Address, City or Town   The Woodlands
Entity Address, State or Province   TX
Entity Address, Postal Zip Code   77381
City Area Code   281
Local Phone Number   863-3000
Title of 12(b) Security   Common Stock, par value $0.001
Trading Symbol   LXRX
Security Exchange Name   NASDAQ
Written Communications   false
Soliciting Material   false
Document Period End Date Nov. 06, 2025  
Amendment Flag   false
Entity Central Index Key   0001062822
Pre-commencement Tender Offer   false
Pre-commencement Issuer Tender Offer   false
Entity Emerging Growth Company   false