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Property, Plant and Equipment and Inventory
 3 Months Ended
Mar. 31, 2022
Property, Plant and Equipment [Abstract]  
Property, Plant and Equipment and Inventory Property, Plant and Equipment and Inventory
Property, plant and equipment
Property, plant and equipment is comprised of the following at March 31, 2022 and December 31, 2021 (in thousands):
March 31, 2022December 31, 2021
Machinery and equipment$208,231 $206,919 
Furniture, fixtures and other55,753 52,794 
Leasehold improvements57,577 56,988 
Buildings and land13,345 13,345 
Construction in process19,971 15,340 
354,877 345,386 
Less: accumulated depreciation(175,700)(166,993)
Total$179,177 $178,393 
Depreciation expense was $9.9 million and $8.6 million for the three months ended March 31, 2022 and March 31, 2021, respectively.
Inventory
Inventory is comprised of the following at March 31, 2022 and December 31, 2021 (in thousands):
March 31, 2022December 31, 2021
Raw materials $106,966 $105,654 
Work-in-process37,003 27,026 
Finished goods497,393 457,274 
Less: obsolescence reserve(24,203)(27,870)
Total$617,159 $562,084