POWER OF ATTORNEY





 The undersigned hereby constitutes and appoints Philip D. Ankeny,

David C. Grorud and Melodie R. Rose ("Attorney-in-Fact"), or any one of

them acting alone, the undersigned's true and lawful attorney-in-fact and

agent with full power of substitution and resubstitution, for the undersigned

and in the undersigned's name, place and stead, in any and all capacities, to

sign any or all Forms 4 or Forms 5 relating to beneficial ownership of

securities of SurModics (the "Issuer"), to file the same, with all exhibits

thereto and other documents in connection therewith, with the Securities and

Exchange Commission and to deliver a copy of the same to the Issuer,

granting unto said attorney-in-fact and agent full power and authority to do

and perform each and every act and thing requisite and necessary to be done

in and about the premises, as fully to all intents and purposes as the

undersigned might or could do in person, hereby ratifying and confirming all

said attorney-in-fact and agent, or his substitute or substitutes, may lawfully

do or cause to be done by virtue thereof.  The undersigned acknowledges

that the foregoing attorney-in-fact, in serving in such capacity at the request

of the undersigned, is not assuming any of the undersigned's responsibilities

to comply with Section 16 of the Securities Exchange Act of 1934.



 This Power of Attorney shall remain in effect until such time as the

undersigned is no longer subject to the provisions of Section 16 of the

Securities Exchange Act of 1934 with respect to securities of the Issuer or

until this Power of Attorney is replaced by a later dated Power of Attorney or

revoked by the undersigned in writing.



 The undersigned hereby indemnifies the Attorneys-in-Fact for all

losses and costs the Attorneys-in-Fact may incur in connection with or

arising from the Attorneys-in-Fact's execution of their authorities granted

hereunder.



 IN WITNESS WHEREOF, the undersigned has caused this Power of

Attorney to be executed as of this 17th day of November, 2003.





      /s/ Patrick E. Guire

     Patrick E. Guire