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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 9 Months Ended
Sep. 30, 2020
Sep. 30, 2019
Operating activities    
Net loss $ (34,994) $ (52,105)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 2,988 3,484
Stock-based compensation expense 10,358 8,292
Amortization of developed technology 8,929 8,400
Amortization of debt discounts, premiums and issuance costs 415 2,130
Lease amortization 1,863 (371)
Loss on extinguishment of debt 0 9,000
Provision for excess and obsolete inventory 680 1,356
Loss on disposal of property and equipment 191 52
Other non-cash items 13 195
Changes in assets and liabilities:    
Accounts receivable, net 967 3,195
Inventories (6,773) (3,672)
Prepaid expenses and other assets (2,395) (1,338)
Accounts payable 4,996 605
Deferred revenue 1,258 1,592
Other liabilities (180) (10,506)
Net cash used in operating activities (11,684) (29,691)
Investing activities    
Acquisition, net of cash acquired (5,154) 0
Purchases of investments 0 (52,719)
Proceeds from RADx grant 11,151 0
Proceeds from sale of investments 5,010 0
Proceeds from maturities of investments 31,800 16,000
Purchases of property and equipment (2,010) (2,031)
Net cash provided by (used in) investing activities 40,797 (38,750)
Financing activities    
Proceeds from issuance of common stock from at-the-market offering, net of commissions 20,226 0
Payment of debt and equity issuance costs (509) (128)
Proceeds from exercise of stock options 450 1,049
Proceeds from stock issuance from ESPP 645 641
Payments for taxes related to net share settlement of equity awards and other (387) (556)
Net cash provided by financing activities 20,425 1,006
Effect of foreign exchange rate fluctuations on cash and cash equivalents 86 (5)
Net increase (decrease) in cash, cash equivalents and restricted cash 49,624 (67,440)
Cash, cash equivalents and restricted cash at beginning of period 23,736 95,401
Cash, cash equivalents and restricted cash at end of period 73,360 27,961
Supplemental disclosures of cash flow information    
Cash paid for interest 86 3,513
Cash paid for income taxes, net of refunds 386 128
Asset retirement obligations $ 319 $ 311