<SEC-DOCUMENT>0001571049-15-005770.txt : 20150722
<SEC-HEADER>0001571049-15-005770.hdr.sgml : 20150722
<ACCEPTANCE-DATETIME>20150722161023
ACCESSION NUMBER:		0001571049-15-005770
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20150721
FILED AS OF DATE:		20150722
DATE AS OF CHANGE:		20150722

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Semler Scientific, Inc.
		CENTRAL INDEX KEY:			0001554859
		STANDARD INDUSTRIAL CLASSIFICATION:	ELECTROMEDICAL & ELECTROTHERAPEUTIC APPARATUS [3845]
		IRS NUMBER:				261367393
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		2330 N.W. EVERETT STREET
		CITY:			PORTLAND
		STATE:			OR
		ZIP:			97210
		BUSINESS PHONE:		408-627-4557

	MAIL ADDRESS:	
		STREET 1:		2330 N.W. EVERETT STREET
		CITY:			PORTLAND
		STATE:			OR
		ZIP:			97210

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			McRae Robert
		CENTRAL INDEX KEY:			0001306323

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-36305
		FILM NUMBER:		151000092

	MAIL ADDRESS:	
		STREET 1:		C/O SEMLER SCIENTIFIC, INC.
		STREET 2:		2330 NW EVERETT ST.
		CITY:			PORTLAND
		STATE:			OR
		ZIP:			97210
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>t1501678_mcrae-4.xml
<DESCRIPTION>OWNERSHIP DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0306</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2015-07-21</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001554859</issuerCik>
        <issuerName>Semler Scientific, Inc.</issuerName>
        <issuerTradingSymbol>SMLR</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001306323</rptOwnerCik>
            <rptOwnerName>McRae Robert</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O SEMLER SCIENTIFIC</rptOwnerStreet1>
            <rptOwnerStreet2>2230 NW EVERETT ST.</rptOwnerStreet2>
            <rptOwnerCity>PORTLAND</rptOwnerCity>
            <rptOwnerState>OR</rptOwnerState>
            <rptOwnerZipCode>97210</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>President and COO</officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Stock Option (right to buy)</value>
                <footnoteId id="F1"/>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>3.44</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2015-07-21</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionTimeliness></transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>10000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2025-07-21</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>10000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>10000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">This option was granted under the issuer's 2014 Stock Incentive Plan. The option is subject to monthly vesting over four years (1/48 per month) such that it is vested in full on the four-year anniversary of its grant date.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Daniel E. Conger, attorney in fact</signatureName>
        <signatureDate>2015-07-22</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
