<SEC-DOCUMENT>0001011712-25-000018.txt : 20250814
<SEC-HEADER>0001011712-25-000018.hdr.sgml : 20250814
<ACCEPTANCE-DATETIME>20250814103229
ACCESSION NUMBER:		0001011712-25-000018
CONFORMED SUBMISSION TYPE:	SCHEDULE 13G/A
PUBLIC DOCUMENT COUNT:		2
FILED AS OF DATE:		20250814
DATE AS OF CHANGE:		20250814

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Semler Scientific, Inc.
		CENTRAL INDEX KEY:			0001554859
		STANDARD INDUSTRIAL CLASSIFICATION:	ELECTROMEDICAL & ELECTROTHERAPEUTIC APPARATUS [3845]
		ORGANIZATION NAME:           	08 Industrial Applications and Services
		EIN:				261367393
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-88028
		FILM NUMBER:		251215344

	BUSINESS ADDRESS:	
		STREET 1:		51 E CAMPBELL AVE
		STREET 2:		SUITE 107-D
		CITY:			CAMPBELL
		STATE:			CA
		ZIP:			95008
		BUSINESS PHONE:		8777744211

	MAIL ADDRESS:	
		STREET 1:		51 E CAMPBELL AVE
		STREET 2:		SUITE 107-D
		CITY:			CAMPBELL
		STATE:			CA
		ZIP:			95008

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			CAPITAL VENTURES INTERNATIONAL
		CENTRAL INDEX KEY:			0001011712
		ORGANIZATION NAME:           	
		EIN:				980158206
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		WINDWARD 1
		STREET 2:		REGATTA OFFICE PARK, WEST BAY ROAD
		CITY:			GRAND CAYMAN
		STATE:			E9
		ZIP:			KY1-1103
		BUSINESS PHONE:		345-949-7576

	MAIL ADDRESS:	
		STREET 1:		WINDWARD 1
		STREET 2:		REGATTA OFFICE PARK, WEST BAY ROAD
		CITY:			GRAND CAYMAN
		STATE:			E9
		ZIP:			KY1-1103

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CAPITAL VENTURES INTERNATIONAL /E9/
		DATE OF NAME CHANGE:	19960403
</SEC-HEADER>
<DOCUMENT>
<TYPE>SCHEDULE 13G/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>SCHEDULE 13G/A</submissionType>
    <previousAccessionNumber>0001011712-25-000006</previousAccessionNumber>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001011712</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <amendmentNo>2</amendmentNo>
      <securitiesClassTitle>Common Stock, $0.001 par value per share</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>06/30/2025</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001554859</issuerCik>
        <issuerName>Semler Scientific, Inc.</issuerName>
        <issuerCusip>81684M104</issuerCusip>
        <issuerPrincipalExecutiveOfficeAddress>
          <com:street1>51 E Campbell Ave </com:street1>
          <com:street2>Suite 107-D</com:street2>
          <com:city>Campbell</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>95008</com:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(c)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>Capital Ventures International</reportingPersonName>
      <citizenshipOrOrganization>E9</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>181494</soleVotingPower>
        <sharedVotingPower>597196</sharedVotingPower>
        <soleDispositivePower>181494</soleDispositivePower>
        <sharedDispositivePower>597196</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>597196</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>4.4</classPercent>
      <typeOfReportingPerson>CO</typeOfReportingPerson>
      <comments>With respect to Row 5 through Row 9 above, G1 Execution Services, LLC, SIG Brokerage, LP and Susquehanna Securities, LLC are affiliated independent broker-dealers which, together with Capital Ventures International and Susquehanna Advisors Group, Inc., may be deemed a group.  For purposes of this report, we have indicated that each reporting person has sole voting and dispositive power with respect to the shares beneficially owned by it and that the reporting persons have shared voting and dispositive power with respect to all shares beneficially owned by all of the reporting persons.  Each of the reporting persons disclaims beneficial ownership of shares owned directly by another reporting person. With respect to Row 5 and Row 7 above, Susquehanna Advisors Group, Inc. is the investment manager to Capital Ventures International and as such may exercise voting and dispositive power over the shares directly owned by Capital Ventures International.</comments>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>Susquehanna Advisors Group, Inc.</reportingPersonName>
      <citizenshipOrOrganization>PA</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0</soleVotingPower>
        <sharedVotingPower>597196</sharedVotingPower>
        <soleDispositivePower>0</soleDispositivePower>
        <sharedDispositivePower>597196</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>597196</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <classPercent>4.4</classPercent>
      <typeOfReportingPerson>CO</typeOfReportingPerson>
      <comments>With respect to Row 5 through Row 9 above, G1 Execution Services, LLC, SIG Brokerage, LP and Susquehanna Securities, LLC are affiliated independent broker-dealers which, together with Capital Ventures International and Susquehanna Advisors Group, Inc., may be deemed a group.  For purposes of this report, we have indicated that each reporting person has sole voting and dispositive power with respect to the shares beneficially owned by it and that the reporting persons have shared voting and dispositive power with respect to all shares beneficially owned by all of the reporting persons.  Each of the reporting persons disclaims beneficial ownership of shares owned directly by another reporting person. With respect to Row 5 and Row 7 above, Susquehanna Advisors Group, Inc. is the investment manager to Capital Ventures International and as such may exercise voting and dispositive power over the shares directly owned by Capital Ventures International.</comments>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>G1 Execution Services, LLC</reportingPersonName>
      <citizenshipOrOrganization>IL</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>4936</soleVotingPower>
        <sharedVotingPower>597196</sharedVotingPower>
        <soleDispositivePower>4936</soleDispositivePower>
        <sharedDispositivePower>597196</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>597196</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <classPercent>4.4</classPercent>
      <typeOfReportingPerson>BD</typeOfReportingPerson>
      <typeOfReportingPerson>OO</typeOfReportingPerson>
      <comments>With respect to Row 5 through Row 9 above, G1 Execution Services, LLC, SIG Brokerage, LP and Susquehanna Securities, LLC are affiliated independent broker-dealers which, together with Capital Ventures International and Susquehanna Advisors Group, Inc., may be deemed a group.  For purposes of this report, we have indicated that each reporting person has sole voting and dispositive power with respect to the shares beneficially owned by it and that the reporting persons have shared voting and dispositive power with respect to all shares beneficially owned by all of the reporting persons.  Each of the reporting persons disclaims beneficial ownership of shares owned directly by another reporting person. </comments>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>SIG Brokerage, LP</reportingPersonName>
      <citizenshipOrOrganization>DE</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>12551</soleVotingPower>
        <sharedVotingPower>597196</sharedVotingPower>
        <soleDispositivePower>12551</soleDispositivePower>
        <sharedDispositivePower>597196</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>597196</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <classPercent>4.4</classPercent>
      <typeOfReportingPerson>BD</typeOfReportingPerson>
      <typeOfReportingPerson>PN</typeOfReportingPerson>
      <comments>With respect to Row 5 through Row 9 above, G1 Execution Services, LLC, SIG Brokerage, LP and Susquehanna Securities, LLC are affiliated independent broker-dealers which, together with Capital Ventures International and Susquehanna Advisors Group, Inc., may be deemed a group.  For purposes of this report, we have indicated that each reporting person has sole voting and dispositive power with respect to the shares beneficially owned by it and that the reporting persons have shared voting and dispositive power with respect to all shares beneficially owned by all of the reporting persons.  Each of the reporting persons disclaims beneficial ownership of shares owned directly by another reporting person. </comments>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>Susquehanna Securities, LLC</reportingPersonName>
      <citizenshipOrOrganization>DE</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>398215</soleVotingPower>
        <sharedVotingPower>597196</sharedVotingPower>
        <soleDispositivePower>398215</soleDispositivePower>
        <sharedDispositivePower>597196</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>597196</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <classPercent>4.4</classPercent>
      <typeOfReportingPerson>BD</typeOfReportingPerson>
      <typeOfReportingPerson>OO</typeOfReportingPerson>
      <comments>With respect to Row 5 through Row 9 above, G1 Execution Services, LLC, SIG Brokerage, LP and Susquehanna Securities, LLC are affiliated independent broker-dealers which, together with Capital Ventures International and Susquehanna Advisors Group, Inc., may be deemed a group.  For purposes of this report, we have indicated that each reporting person has sole voting and dispositive power with respect to the shares beneficially owned by it and that the reporting persons have shared voting and dispositive power with respect to all shares beneficially owned by all of the reporting persons.  Each of the reporting persons disclaims beneficial ownership of shares owned directly by another reporting person. </comments>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>Semler Scientific, Inc.</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>51 E Campbell Ave, Suite 107-D, Campbell, CA 95008</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>This statement is filed by the entities listed below, who are collectively referred to herein as "Reporting Persons," with respect to the shares of Common Stock, $0.001 par value per share (the "Shares"), of Semler Scientific, Inc. (the "Company").

(i)         Capital Ventures International
(ii)        Susquehanna Advisors Group, Inc.
(iii)       G1 Execution Services, LLC
(iv)       SIG Brokerage, LP
(v)        Susquehanna Securities, LLC</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>The address of the principal business office of Capital Ventures International is:

P.O. Box 897
Windward 1, Regatta Office Park
West Bay Road
Grand Cayman, KY1-1103
Cayman Islands

The address of the principal business office of G1 Execution Services, LLC is:

175 W. Jackson Blvd.
Suite 1700
Chicago, IL 60604

The address of the principal business office of each of SIG Brokerage, LP, Susquehanna Advisors Group, Inc. and Susquehanna Securities, LLC is:

401 E. City Avenue
Suite 220
Bala Cynwyd, PA 19004</principalBusinessOfficeOrResidenceAddress>
        <citizenship>Citizenship is set forth in Row 4 of the cover page for each Reporting Person hereto and is incorporated herein by reference for each such Reporting Person.</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>Y</notApplicableFlag>
      </item3>
      <item4>
        <amountBeneficiallyOwned>
The information required by this Item 4(a) is set forth in Row 9 of the cover page for each Reporting Person hereto and is incorporated herein by reference for each such Reporting Person.

The number of Shares reported as beneficially owned by Susquehanna Securities, LLC includes options to buy 202,600 Shares.

The Company's Definitive Proxy Statement on Schedule 14A, filed on July 17, 2025, indicates there were 13,688,405 Shares outstanding as of June 30, 2025.</amountBeneficiallyOwned>
        <classPercent>4.4</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>
The information required by this Item 4(c)(i) is set forth in Row 5 of the cover page for each Reporting Person hereto and is incorporated herein by reference for each such Reporting Person.</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>
The information required by this Item 4(c)(ii) is set forth in Row 6 of the cover page for each Reporting Person hereto and is incorporated herein by reference for each such Reporting Person.</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>
The information required by this Item 4(c)(iii) is set forth in Row 7 of the cover page for each Reporting Person hereto and is incorporated herein by reference for each such Reporting Person.</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>
The information required by this Item 4(c)(iv) is set forth in Row 8 of the cover page for each Reporting Person hereto and is incorporated herein by reference for each such Reporting Person. </sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <notApplicableFlag>N</notApplicableFlag>
        <classOwnership5PercentOrLess>Y</classOwnership5PercentOrLess>
      </item5>
      <item6>
        <notApplicableFlag>Y</notApplicableFlag>
      </item6>
      <item7>
        <notApplicableFlag>Y</notApplicableFlag>
      </item7>
      <item8>
        <notApplicableFlag>Y</notApplicableFlag>
      </item8>
      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>N</notApplicableFlag>
        <certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.</certifications>
      </item10>
    </items>
    <exhibitInfo>	EXHIBIT INDEX

EXHIBIT					DESCRIPTION
________				________
24						Limited Power of Attorney*
99						Joint Filing Agreement

* Previously filed
</exhibitInfo>
    <signatureInformation>
      <reportingPersonName>Capital Ventures International</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Brian Sopinsky</signature>
        <title>Brian Sopinsky, Assistant Secretary of Susquehanna Advisors Group, Inc.</title>
        <date>08/13/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Susquehanna Advisors Group, Inc.</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Brian Sopinsky</signature>
        <title>Brian Sopinsky, Assistant Secretary</title>
        <date>08/13/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>G1 Execution Services, LLC</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Brian Sopinsky</signature>
        <title>Brian Sopinsky, Secretary</title>
        <date>08/13/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>SIG Brokerage, LP</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Brian Sopinsky</signature>
        <title>Brian Sopinsky, Assistant Secretary</title>
        <date>08/13/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Susquehanna Securities, LLC</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Brian Sopinsky</signature>
        <title>Brian Sopinsky, Secretary</title>
        <date>08/13/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureComments>Susquehanna Advisors Group, Inc. serves as authorized agent of Capital Ventures International pursuant to a Limited Power of Attorney, a copy of which was previously filed.</signatureComments>
  </formData>

</edgarSubmission>
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</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99
<SEQUENCE>2
<FILENAME>smlr_sc13g-ex99.htm
<DESCRIPTION>JOINT FILING AGREEMENT
<TEXT>
<html><head></head><body style="font: 11pt Times New Roman, Times, Serif"><p style="text-align: end"><b>Exhibit 99</b></p><p style="text-align: center"><b>JOINT FILING AGREEMENT</b></p><p>This will confirm the agreement by and among the undersigned that the Schedule 13G filed with the Securities and Exchange Commission on or about the date hereof with respect to the beneficial ownership by the undersigned of the common stock, $0.001 par value per share, of Semler Scientific, Inc., is being filed, and all amendments thereto will be filed, on behalf of each of the persons and entities named below in accordance with Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended. This Agreement may be executed in two or more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument.</p><p>Dated as of August 13, 2025</p><p>CAPITAL VENTURES INTERNATIONAL</p><p style="margin-bottom: 0">By: Susquehanna Advisors Group, Inc.</p><p style="margin-top: 0">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;pursuant to a Limited Power of Attorney</p><p style="margin: 0">By: <u>/s/ Brian Sopinsky</u></p><p style="margin: 0">Name: Brian Sopinsky</p><p style="margin: 0">Title: Assistant Secretary</p><p>SUSQUEHANNA ADVISORS GROUP, INC.</p><p style="margin: 0">By: <u>/s/ Brian Sopinsky</u></p><p style="margin: 0">Name: Brian Sopinsky</p><p style="margin: 0">Title: Assistant Secretary</p><p>G1 EXECUTION SERVICES, LLC</p><p style="margin: 0">By: <u>/s/ Brian Sopinsky</u></p><p style="margin: 0">Name: Brian Sopinsky</p><p style="margin: 0">Title: Secretary</p><p>SIG BROKERAGE, LP</p><p style="margin: 0">By: <u>/s/ Brian Sopinsky</u></p><p style="margin: 0">Name: Brian Sopinsky</p><p style="margin: 0">Title: Assistant Secretary</p><p>SUSQUEHANNA SECURITIES, LLC</p><p style="margin: 0">By: <u>/s/ Brian Sopinsky</u></p><p style="margin: 0">Name: Brian Sopinsky</p><p style="margin: 0">Title: Secretary</p><p>&nbsp;</p><div style="border-bottom: Black 1pt solid"></div></body></html>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
