<SEC-DOCUMENT>0001104659-25-112464.txt : 20251114
<SEC-HEADER>0001104659-25-112464.hdr.sgml : 20251114
<ACCEPTANCE-DATETIME>20251114160354
ACCESSION NUMBER:		0001104659-25-112464
CONFORMED SUBMISSION TYPE:	SCHEDULE 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20251114
DATE AS OF CHANGE:		20251114

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Semler Scientific, Inc.
		CENTRAL INDEX KEY:			0001554859
		STANDARD INDUSTRIAL CLASSIFICATION:	ELECTROMEDICAL & ELECTROTHERAPEUTIC APPARATUS [3845]
		ORGANIZATION NAME:           	08 Industrial Applications and Services
		EIN:				261367393
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-88028
		FILM NUMBER:		251485691

	BUSINESS ADDRESS:	
		STREET 1:		51 E CAMPBELL AVE
		STREET 2:		SUITE 107-D
		CITY:			CAMPBELL
		STATE:			CA
		ZIP:			95008
		BUSINESS PHONE:		8777744211

	MAIL ADDRESS:	
		STREET 1:		51 E CAMPBELL AVE
		STREET 2:		SUITE 107-D
		CITY:			CAMPBELL
		STATE:			CA
		ZIP:			95008

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Ridgeback Capital Investments L.P.
		CENTRAL INDEX KEY:			0001423994
		ORGANIZATION NAME:           	
		EIN:				000000000
		STATE OF INCORPORATION:			E9
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		30 STAR ISLAND DRIVE
		CITY:			MIAMI BEACH
		STATE:			FL
		ZIP:			33139
		BUSINESS PHONE:		212-808-7729

	MAIL ADDRESS:	
		STREET 1:		30 STAR ISLAND DRIVE
		CITY:			MIAMI BEACH
		STATE:			FL
		ZIP:			33139
</SEC-HEADER>
<DOCUMENT>
<TYPE>SCHEDULE 13G/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>SCHEDULE 13G/A</submissionType>
    <previousAccessionNumber>0001104659-25-068265</previousAccessionNumber>
    <filerInfo>
      <filer>
        <filerCredentials>
          <!-- Field: Pseudo-Tag; ID: Name; Data: Ridgeback Capital Investments L.P. -->
          <cik>0001423994</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <amendmentNo>1</amendmentNo>
      <securitiesClassTitle>Common stock, par value $0.001 per share</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>09/30/2025</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001554859</issuerCik>
        <issuerName>Semler Scientific, Inc.</issuerName>
        <issuerCusip>81684M104</issuerCusip>
        <issuerPrincipalExecutiveOfficeAddress>
          <com:street1>51 E. Campbell Ave.</com:street1>
          <com:street2>Suite 107-D</com:street2>
          <com:city>Campbell</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>95008</com:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(c)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>Ridgeback Capital Investments L.P.</reportingPersonName>
      <citizenshipOrOrganization>DE</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>0.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>0.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>0.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>0.0</classPercent>
      <typeOfReportingPerson>OO</typeOfReportingPerson>
      <comments>The percentages used herein are calculated based upon 14,804,693 shares of common stock outstanding as of July 31, 2025, as reported by the Company in its Quarterly Report on Form 10-Q filed with the SEC on August 4, 2025.</comments>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>Ridgeback Capital Investments LLC</reportingPersonName>
      <citizenshipOrOrganization>DE</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>0.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>0.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>0.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>0.0</classPercent>
      <typeOfReportingPerson>OO</typeOfReportingPerson>
      <comments>The percentages used herein are calculated based upon 14,804,693 shares of common stock outstanding as of July 31, 2025, as reported by the Company in its Quarterly Report on Form 10-Q filed with the SEC on August 4, 2025.</comments>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>Ridgeback Capital Management LLC</reportingPersonName>
      <citizenshipOrOrganization>DE</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>0.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>0.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>0.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>0.0</classPercent>
      <typeOfReportingPerson>OO</typeOfReportingPerson>
      <comments>The percentages used herein are calculated based upon 14,804,693 shares of common stock outstanding as of July 31, 2025, as reported by the Company in its Quarterly Report on Form 10-Q filed with the SEC on August 4, 2025.</comments>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>Semler Scientific, Inc.</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>51 E. Campbell Ave., Suite 107-D, Campbell, CA, 95008</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>This statement is filed on behalf of the following persons with respect to shares of common stock of the Company acquired by them (the "Shares"):

(i)   Ridgeback Capital Investments L.P., Delaware limited partnership ("RCILP"), with respect to Shares beneficially owned by it;

(ii)  Ridgeback Capital Investments LLC, a Delaware limited liability company ("RCI"), with respect to Shares beneficially owned by it; and

(iii) Ridgeback Capital Management LLC, a Delaware limited liability company ("RCM"), with respect to Shares beneficially owned by it.

The foregoing persons are hereinafter referred to collectively as the "Reporting Persons."  Any disclosures herein with respect to persons other than the Reporting Persons are made on information and belief after making inquiry to the appropriate party.

RCM and RCI do not own any Shares directly.  RCI is the general partner of RCILP.  Pursuant to an investment management agreement, RCM maintains investment and voting power with respect to the securities held or controlled by RCI.  Wayne Holman, an individual, controls RCM. By reason of the provisions of Rule 13d-3 of the Securities Exchange Act of 1934, as amended, RCM and RCI may be deemed to own beneficially all of the Shares (constituting approximately 6.9% of the shares outstanding).  Each of RCM and RCI disclaim beneficial ownership of any of the securities covered by this statement, except to the extent of any pecuniary interest therein.</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>30 Star Island Drive, Miami, FL, 33139</principalBusinessOfficeOrResidenceAddress>
        <citizenship>RCILP is a Delaware limited partnership.  RCI is a Delaware limited liability company.  RCM is a Delaware limited liability company.</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>Y</notApplicableFlag>
      </item3>
      <item4>
        <amountBeneficiallyOwned>Ridgeback Capital Investments L.P.: -0-
Ridgeback Capital Investments LLC: -0-
Ridgeback Capital Management LLC: -0-</amountBeneficiallyOwned>
        <classPercent>Ridgeback Capital Investments L.P.: 0.0%
Ridgeback Capital Investments LLC: 0.0%
Ridgeback Capital Management LLC: 0.0%</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>Ridgeback Capital Investments L.P.: -0-
Ridgeback Capital Investments LLC: -0-
Ridgeback Capital Management LLC: -0-</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>Ridgeback Capital Investments L.P.: -0-
Ridgeback Capital Investments LLC: -0-
Ridgeback Capital Management LLC: -0-</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>Ridgeback Capital Investments L.P.: -0-
Ridgeback Capital Investments LLC: -0-
Ridgeback Capital Management LLC: -0-</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>Ridgeback Capital Investments L.P.: -0-
Ridgeback Capital Investments LLC: -0-
Ridgeback Capital Management LLC: -0-</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <notApplicableFlag>N</notApplicableFlag>
        <classOwnership5PercentOrLess>Y</classOwnership5PercentOrLess>
      </item5>
      <item6>
        <notApplicableFlag>Y</notApplicableFlag>
      </item6>
      <item7>
        <notApplicableFlag>Y</notApplicableFlag>
      </item7>
      <item8>
        <notApplicableFlag>Y</notApplicableFlag>
      </item8>
      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>N</notApplicableFlag>
        <certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.</certifications>
      </item10>
    </items>
    <exhibitInfo>Exhibit Number 99.1 - Joint Filing Agreement - previously filed</exhibitInfo>
    <signatureInformation>
      <reportingPersonName>Ridgeback Capital Investments L.P.</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Nicole Venezia</signature>
        <title>Nicole Venezia/General Counsel</title>
        <date>11/14/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Ridgeback Capital Investments LLC</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Nicole Venezia</signature>
        <title>Nicole Venezia/General Counsel</title>
        <date>11/14/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Ridgeback Capital Management LLC</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Nicole Venezia</signature>
        <title>Nicole Venezia/General Counsel</title>
        <date>11/14/2025</date>
      </signatureDetails>
    </signatureInformation>
  </formData>
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</SEC-DOCUMENT>
