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Stockholders' equity (Tables) | 12 Months Ended
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Dec. 31, 2016
Stockholders' equity [Abstract] |
Option award activity | The following is a summary of option award activity under the Emergent Plans:
|  | 2006 Plan |  |  | 2004 Plan |  |  |  |
|  | Number of Shares |  |  | Weighted-Average Exercise Price |  |  | Number of Shares |  |  | Weighted-Average Exercise Price |  |  | Aggregate Intrinsic Value |
Outstanding at December 31, 2015 |  |  | 2,964,237 |  |  | $ | 22.73 |  |  |  | 29,699 |  |  | $ | 10.28 |  |  | $ | 52,119,607 |
Granted |  |  | 411,698 |  |  |  | 33.61 |  |  |  | - |  |  |  | - |  |  |  |  |
Exercised |  |  | (809,638 | ) |  |  | 19.41 |  |  |  | (29,699 | ) |  |  | 10.28 |  |  |  |  |
Forfeited |  |  | (96,293 | ) |  |  | 26.67 |  |  |  | - |  |  |  | - |  |  |  |  |
Cancelled |  |  | (146,986 | ) |  |  | 28.33 |  |  |  | - |  |  |  | - |  |  |  |  |
Equitable adjustment |  |  | 236,313 |  |  |  | 22.90 |  |  |  | - |  |  |  | - |  |  |  |  |
Outstanding at December 31, 2016 |  |  | 2,559,331 |  |  | $ | 22.94 |  |  |  | - |  |  | $ | - |  |  | $ | 25,348,245 |
Exercisable at December 31, 2016 |  |  | 1,504,855 |  |  | $ | 19.59 |  |  |  | - |  |  | $ | - |  |  | $ | 19,938,451 |
Options expected to vest at December 31, 2016 |  |  | 849,184 |  |  | $ | 27.46 |  |  |  | - |  |  | $ | - |  |  | $ | 4,565,548 |
Restricted stock units activity | The following is a summary of restricted stock unit award activity under the 2006 Plan:
|  | Number of Shares |  |  | Weighted-Average Grant Price |  |  | Aggregate Intrinsic Value |
Outstanding at December 31, 2015 |  |  | 889,004 |  |  | $ | 26.86 |  |  | $ | 35,569,048 |
Granted |  |  | 515,782 |  |  |  | 34.00 |  |  |  |  |
Vested |  |  | (420,599 | ) |  |  | 24.68 |  |  |  |  |
Forfeited |  |  | (80,428 | ) |  |  | 29.40 |  |  |  |  |
Cancelled |  |  | (107,514 | ) |  |  | 30.90 |  |  |  |  |
Equitable adjustment |  |  | 79,339 |  |  |  | 28.86 |  |  |  |  |
Outstanding at December 31, 2016 |  |  | 875,584 |  |  | $ | 28.94 |  |  | $ | 28,754,179 |
Allocated stock-based compensation expense | Stock-based compensation expense was recorded in the following financial statement line items:
|  | Years ended December 31, |
(in thousands) |  | 2016 |  |  | 2015 |  |  | 2014 |
Cost of product sales |  | $ | 997 |  |  | $ | 1,183 |  |  | $ | 1,145 |
Research and development |  |  | 2,297 |  |  |  | 2,324 |  |  |  | 2,779 |
Selling, general and administrative |  |  | 14,062 |  |  |  | 11,234 |  |  |  | 7,830 |
Continuing operations |  |  | 17,356 |  |  |  | 14,741 |  |  |  | 11,754 |
Discontinued operations |  |  | 1,121 |  |  |  | 1,107 |  |  |  | 1,075 |
Total stock-based compensation expense |  | $ | 18,477 |  |  | $ | 15,848 |  |  | $ | 12,829 |

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