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Discontinued operations (Details) - USD ($) $ in Thousands |  | 12 Months Ended
--- | --- | ---
Aug. 01, 2016 | Dec. 31, 2016 | Dec. 31, 2015
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items] |  |  |
Percentage of outstanding shares distributed | 100.00% |  |
Record date for distribution | Jul. 22, 2016 |  |
Number of shares received (in shares) | 1 |  |
Number of shares held (in shares) | 2 |  |
Number of common stock distributed (in shares) | 20,230,000 |  |
Aptevo [Member] |  |  |
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items] |  |  |
Unsecured debt | $ 20,000 |  |
Revenues [Abstract] |  |  |
Product sales |  | $ 21,183 | $ 27,947
Collaborations |  | 187 | 5,511
Total revenues |  | 21,370 | 33,458
Operating expense [Abstract] |  |  |
Cost of product sales |  | 11,556 | 16,809
Research and development |  | 18,024 | 34,811
Selling, general and administrative |  | 23,792 | 27,313
Loss from operations |  | (32,002) | (45,475)
Other income (expense), net [Abstract] |  |  |
Other income (expense), net |  | (41) | (472)
Loss from discontinued operations before benefit from income taxes |  | (32,043) | (45,947)
Benefit from income taxes |  | (21,295) | (17,401)
Net loss from discontinued operations |  | (10,748) | (28,546)
Net Cash Provided by (Used in) Discontinued Operations [Abstract] |  |  |
Net cash used in operating activities |  | (10,299) | (12,716)
Net cash used in investing activities |  | (1,926) | (1,518)
Net cash provided by financing activities |  | 7,733 | 15,012
Net increase (decrease) in cash and cash equivalents |  | $ (4,492) | $ 778

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