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Intangible assets and goodwill
12 Months Ended
Dec. 31, 2017
Intangible assets and goodwill [Abstract]  
Intangible assets and goodwill
9. Intangible assets and goodwill

As of October 1, 2017 and 2016, the Company performed a qualitative assessment of goodwill associated with the Therapeutics and Vaccines reporting unit, Contract Manufacturing reporting unit, and the Devices reporting unit and determined there were no indicators of impairment.

Intangible assets consisted of the following:

    
(in thousands) 
 
Total
 
Cost basis
   
Balance at December 31, 2016
 
$
57,099
 
Additions
  
94,304
 
Balance at December 31, 2017
 
$
151,403
 
     
Accumulated amortization
    
Balance at December 31, 2016
 
$
(23,234
)
Amortization
  
(8,572
)
Balance at December 31, 2017
 
$
(31,806
)
     
Net book value at December 31, 2017
 
$
119,597
 

For the years ended December 31, 2017, 2016 and 2015, the Company recorded amortization expense of $8.6 million, $6.9 million and $7.4 million, respectively, for intangible assets, which has been recorded in operating expenses, specifically selling, general and administrative and cost of product sales and contract manufacturing. As of December 31, 2017, the weighted average amortization period remaining for intangible assets is 105 months.

Future amortization expense as of December 31, 2017 is as follows:

(in thousands)
   
2018
 
$
15,647
 
2019
  
15,168
 
2020
  
15,087
 
2021
  
13,596
 
2022 and beyond
  
60,099
 
Total remaining amortization
 
$
119,597
 

The following table is a summary of changes in goodwill by reporting unit:

(in thousands) 
 
Therapeutics and vaccines
  
Contract manufacturing
  
Devices
  
Total
 
Cost Basis
            
Balance at December 31, 2016
 
$
24,349
  
$
6,736
  
$
9,916
  
$
41,001
 
Additions
  
8,129
   
-
   
-
   
8,129
 
Balance at December 31, 2017
 
$
32,478
  
$
6,736
  
$
9,916
  
$
49,130