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Subsequent events, Acquisitions (Details) - Subsequent Event [Member] | Oct. 15, 2018 USD ($) Employee $ / shares shares | Oct. 04, 2018 USD ($) Employee
--- | --- | ---
PaxVax [Member] |  |
Subsequent Event [Line Items] |  |
Number of employees | Employee |  | 250
Cash paid for acquisition |  | $ 270,000,000
Adapt Pharma [Member] |  |
Subsequent Event [Line Items] |  |
Number of employees | Employee | 50 |
Cash paid for acquisition | $ 575,000,000 |
Common stock issued for acquisition (in shares) | shares | 733,309 |
Number of trading days considered to determine share price for acquisition | 10 days |
Number of trading days before closing to determine share price for acquisition | 2 days |
Share price (in dollars per share) | $ / shares | $ 65.28 |
Amount of common stock issued for acquisition including adjustments | $ 47,870,412 |
Adapt Pharma [Member] | Maximum [Member] |  |
Subsequent Event [Line Items] |  |
Remaining consideration payable for acquisition cash amount | $ 100,000,000 |

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