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Acquisitions (Details) - USD ($) $ in Thousands | Oct. 06, 2017 | Sep. 30, 2018 | Dec. 31, 2017
--- | --- | --- | ---
Fair value of tangible assets acquired and liabilities assumed [Abstract] |  |  |
Goodwill |  | $ 49,130 | $ 49,130
Sanofi [Member] |  |  |
Summary of total purchase price [Abstract] |  |  |
Amount of cash paid to Sanofi | $ 117,500 |  |
Fair value of contingent purchase consideration | 2,200 |  |
Total purchase price | 119,700 |  |
Fair value of tangible assets acquired and liabilities assumed [Abstract] |  |  |
Inventory | 74,876 |  |
Property, plant and equipment | 19,995 |  |
Total fair value of tangible assets acquired and liabilities assumed | 94,871 |  |
Acquired intangible asset | 16,700 |  |
Goodwill | 8,129 |  |
Total purchase price | $ 119,700 |  |
ACAM2000 [Member] |  |  |
Acquisitions [Abstract] |  |  |
Term of contract under acquisition | 10 years |  |
Value of contract | $ 425,000 |  |
Amount for deliveries of product to the SNS | 160,000 |  |
Upfront cash payment | 97,500 |  |
Amount of payment for manufacturing related milestones | 20,000 |  |
Amount of payment for regulatory related milestones | $ 7,500 |  | $ 7,500
Fair value of tangible assets acquired and liabilities assumed [Abstract] |  |  |
Amortization period of intangible asset | 10 years |  |
ACAM2000 [Member] | Discount Rate [Member] |  |  |
Fair value of tangible assets acquired and liabilities assumed [Abstract] |  |  |
Present value discount rate | 15.50% |  |

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