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Equity - Schedule of Stock-based Compensation Expense (Details) - USD ($) $ in Millions | 3 Months Ended | 6 Months Ended
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Jun. 30, 2021 | Jun. 30, 2020 | Jun. 30, 2021 | Jun. 30, 2020
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] |  |  |  |
Total share-based compensation expense | $ 11.4 | $ 24.4 | $ 21.9 | $ 31.0
Cost of product sales and contract development and manufacturing services |  |  |  |
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] |  |  |  |
Total share-based compensation expense | 2.0 | 8.1 | 3.7 | 8.8
Research and development |  |  |  |
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] |  |  |  |
Total share-based compensation expense | 1.7 | 5.4 | 3.1 | 6.3
Selling, general and administrative |  |  |  |
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] |  |  |  |
Total share-based compensation expense | $ 7.7 | $ 10.9 | $ 15.1 | $ 15.9

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