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Property, plant and equipment, net
 3 Months Ended
Mar. 31, 2022
Property Plant and Equipment Income Statement Disclosures [Abstract]  
Property, plant and equipment Property, plant and equipment, net
Property, plant and equipment, net consisted of the following:
March 31, 2022December 31, 2021
Land and improvements$51.9 $52.1 
Buildings, building improvements and leasehold improvements286.9 269.7 
Furniture and equipment527.9 513.5 
Software62.5 60.7 
Construction-in-progress208.1 223.2 
Property, plant and equipment, gross$1,137.3 $1,119.2 
Less: Accumulated depreciation & amortization(329.8)(319.1)
Total property, plant and equipment, net$807.5 $800.1 
As of March 31, 2022 and December 31, 2021, construction-in-progress primarily includes costs incurred related to construction to advance the Company's CDMO capabilities.