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Property, plant and equipment, net
 6 Months Ended
Jun. 30, 2022
Property Plant and Equipment Income Statement Disclosures [Abstract]  
Property, plant and equipment, net Property, plant and equipment, net
Property, plant and equipment, net consisted of the following:
June 30, 2022December 31, 2021
Land and improvements$51.2 $52.1 
Buildings, building improvements and leasehold improvements293.0 269.7 
Furniture and equipment527.3 513.5 
Software66.2 60.7 
Construction-in-progress218.4 223.2 
Property, plant and equipment, gross$1,156.1 $1,119.2 
Less: Accumulated depreciation & amortization(357.7)(319.1)
Total property, plant and equipment, net$798.4 $800.1 
As of June 30, 2022 and December 31, 2021, construction-in-progress primarily includes costs incurred related to construction to advance the Company's CDMO capabilities.
Property, plant and equipment, net is stated at cost, less accumulated depreciation and amortization. During the three and six months ended June 30, 2022, the Company recorded accelerated depreciation of $12.7 million to shorten the useful life of certain property, plant and equipment which were to be used in the manufacturing process to fulfill the manufacturing services agreement with Janssen. For additional information related to the termination of the Agreement, refer to Note 10, Revenue recognition.