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Equity (Tables)
6 Months Ended
Jun. 30, 2022
Stockholders' Equity Note [Abstract]  
Share-based Payment Arrangement, Expensed and Capitalized, Amount Share-based compensation expense was recorded in the following financial statement line items:
Three Months Ended June 30,Six Months Ended June 30,
2022202120222021
Cost of product sales$1.9 $1.7 $3.6 $3.2 
Cost of contract development and manufacturing0.6 0.3 1.0 0.5 
Research and development1.5 1.7 2.6 3.1 
Selling, general and administrative8.3 7.7 15.0 15.1 
Total share-based compensation expense$12.3 $11.4 $22.2 $21.9 
Schedule of Accumulated Other Comprehensive Income (Loss)
The following table includes changes in accumulated other comprehensive loss, net of tax by component:
Defined Benefit Pension Plan
Derivative InstrumentsForeign Currency Translation AdjustmentsTotal
(in millions, net of tax)
Balance, December 31, 2021
$(4.0)$(4.5)$(7.6)$(16.1)
Other comprehensive income before reclassifications— 6.8 0.9 7.7 
Amounts reclassified from accumulated other comprehensive loss— 2.3 — 2.3 
Net current period other comprehensive income— 9.1 0.9 10.0 
Balance, June 30, 2022
$(4.0)$4.6 $(6.7)$(6.1)
Balance, March 31, 2022
$(4.0)$1.8 $(7.1)$(9.3)
Other comprehensive income before reclassifications— 1.9 0.4 2.3 
Amounts reclassified from accumulated other comprehensive loss— 0.9 — 0.9 
Net current period other comprehensive income— 2.8 0.4 3.2 
Balance, June 30, 2022
$(4.0)$4.6 $(6.7)$(6.1)
Balance, December 31, 2020
$(7.7)$(11.0)$(6.6)$(25.3)
Other comprehensive income (loss) before reclassifications— 1.6 (1.7)(0.1)
Amounts reclassified from accumulated other comprehensive loss— 3.0 — 3.0 
Net current period other comprehensive income (loss)(7.7)4.6 (1.7)2.9 
Balance, June 30, 2021
$(7.7)$(6.4)$(8.3)$(22.4)
Balance, March 31, 2021
$(7.7)$(7.9)$(8.8)$(24.4)
Other comprehensive income (loss) before reclassifications— (0.1)0.5 0.4 
Amounts reclassified from accumulated other comprehensive loss— 1.6 — 1.6 
Net current period other comprehensive incomeNet current period other comprehensive income (loss)— 1.5 0.5 2.0 
Balance, June 30, 2021
$(7.7)$(6.4)$(8.3)$(22.4)
Comprehensive Income (Loss)
The following table presents the tax effects related to each component of other comprehensive income (loss):
Three Months EndedJune 30, 2022June 30, 2021
PretaxTax Benefit (Expense)Net of taxPretaxTax Benefit (Expense)Net of tax
Derivative Instruments3.8 (1.0)2.8 1.2 0.3 1.5 
Foreign Currency Translation Adjustments1.3 (0.9)0.4 0.5 — 0.5 
Total adjustments$5.1 $(1.9)$3.2 $1.7 $0.3 $2.0 
Six Months EndedJune 30, 2022June 30, 2021
PretaxTax Benefit (Expense)Net of taxPretaxTax Benefit (Expense)Net of tax
Derivative Instruments12.4 (3.3)9.1 3.6 1.0 4.6 
Foreign Currency Translation Adjustments2.0 (1.1)0.9 (1.7)— (1.7)
Total adjustments$14.4 $(4.4)$10.0 $1.9 $1.0 $2.9