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Income taxes - Narrative (Details) - USD ($) $ in Millions | 12 Months Ended |
--- | --- | ---
Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019
Income Tax Contingency [Line Items] |  |  |  |
Valuation allowance increase, including CTA component | $ 37.8 |  |  |
Deferred tax liabilities, foreign withholding tax | 4.7 | $ 0.0 |  |
Valuation allowance increase | $ 37.8 |  |  |
Effective income tax rate reconciliation, percent | 3.00% | 28.00% | 26.00% |
Unrecognized tax benefits, noncurrent | $ 6.8 | $ 12.7 |  |
Gross unrecognized tax benefits | 6.8 | 12.7 | $ 12.2 | $ 8.9
Unrecognized tax benefits, reduction resulting from lapse of applicable statute of limitations | 5.1 | 0.0 | 0.0 |
Unrecognized tax benefits, income tax penalties and interest accrued | 1.6 | 3.7 |  |
Unrecognized tax benefits, income tax penalties and interest expense | (2.1) | $ 1.1 | $ 0.4 |
Domestic Tax Authority |  |  |  |
Income Tax Contingency [Line Items] |  |  |  |
Operating loss carryforwards | 70.5 |  |  |
Operating loss carryforwards, subject to expiration | 36.0 |  |  |
Operating loss carryforwards, not subject to expiration | 34.5 |  |  |
Tax credit carryforward, amount | 13.4 |  |  |
State and Local Jurisdiction | Maryland |  |  |  |
Income Tax Contingency [Line Items] |  |  |  |
Operating loss carryforwards | 1,700.0 |  |  |
State and Local Jurisdiction | California |  |  |  |
Income Tax Contingency [Line Items] |  |  |  |
Operating loss carryforwards | 146.5 |  |  |
State and Local Jurisdiction | Research Tax Credit Carryforward |  |  |  |
Income Tax Contingency [Line Items] |  |  |  |
Tax credit carryforward, amount | 5.0 |  |  |
Foreign Tax Authority |  |  |  |
Income Tax Contingency [Line Items] |  |  |  |
Operating loss carryforwards | 51.5 |  |  |
Operating loss carryforwards, subject to expiration | 14.5 |  |  |
Operating loss carryforwards, not subject to expiration | 37.0 |  |  |
PaxVax |  |  |  |
Income Tax Contingency [Line Items] |  |  |  |
Unrecognized tax benefits, reduction resulting from lapse of applicable statute of limitations | $ 8.0 |  |  |

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