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Quarterly financial data - unaudited (Details) - USD ($) $ / shares in Units, $ in Millions	3 Months Ended								12 Months Ended
	Dec. 31, 2022	Sep. 30, 2022	Jun. 30, 2022	Mar. 31, 2022	Dec. 31, 2021	Sep. 30, 2021	Jun. 30, 2021	Mar. 31, 2021	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Error Corrections and Prior Period Adjustments Restatement [Line Items]
Total revenues	$ 330.2	$ 239.9	$ 242.6	$ 304.8	$ 732.9	$ 286.3	$ 377.4	$ 377.0	$ 1,117.5	$ 1,773.6	$ 1,577.3
Cost of goods and services sold									693.1	748.1	537.0
Income (loss) from operations	(55.3)	(45.3)	(76.3)	6.9	286.8	(44.7)	7.1	92.2	(170.0)	341.4	438.5
Net income (loss)	$ (67.0)	$ (87.1)	$ (52.9)	$ (4.6)	$ 193.1	$ (40.4)	$ (0.5)	$ 67.3	$ (211.6)	$ 219.5	$ 305.8
Net income (loss) per common share
Basic (in dollars per share)	$ (1.34)	$ (1.75)	$ (1.06)	$ (0.09)	$ 3.62	$ (0.75)	$ (0.01)	$ 1.26	$ (4.22)	$ 4.10	$ 5.80
Diluted (in dollars per share)	$ (1.34)	$ (1.75)	$ (1.06)	$ (0.09)	$ 3.60	$ (0.75)	$ (0.01)	$ 1.23	$ (4.22)	$ 4.06	$ 5.68
Product sales, net
Error Corrections and Prior Period Adjustments Restatement [Line Items]
Cost of goods and services sold	$ 167.8	$ 85.2	$ 92.2	$ 79.4	$ 144.1	$ 104.3	$ 81.4	$ 52.8	$ 424.6	$ 382.6	$ 392.0
Total CDMO
Error Corrections and Prior Period Adjustments Restatement [Line Items]
Cost of goods and services sold	52.7	62.0	79.8	74.0	69.7	77.5	133.9	84.4	268.5	365.5	145.0
Previously Reported
Error Corrections and Prior Period Adjustments Restatement [Line Items]
Total revenues	330.7	240.0	242.7	307.5	723.2	329.0	397.5	343.0	1,120.9	1,792.7	1,555.4
Income (loss) from operations	(65.1)	(42.0)	(72.0)	6.4	277.4	(34.7)	14.5	95.4	(172.7)	352.6	433.8
Net income (loss)	$ (88.0)	$ (75.7)	$ (56.4)	$ (3.7)	$ 189.3	$ (32.7)	$ 4.6	$ 69.7	$ (223.8)	$ 230.9	$ 305.1
Net income (loss) per common share
Basic (in dollars per share)	$ (1.76)	$ (1.52)	$ (1.13)	$ (0.07)	$ 3.55	$ (0.61)	$ 0.09	$ 1.31	$ (4.47)	$ 4.32	$ 5.79
Diluted (in dollars per share)	$ (1.76)	$ (1.52)	$ (1.13)	$ (0.07)	$ 3.53	$ (0.61)	$ 0.09	$ 1.28	$ (4.47)	$ 4.27	$ 5.67
Previously Reported | Product sales, net
Error Corrections and Prior Period Adjustments Restatement [Line Items]
Cost of goods and services sold	$ 167.3	$ 85.5	$ 91.0	$ 80.3	$ 145.0	$ 103.2	$ 81.2	$ 52.6	$ 424.1	$ 382.0	$ 392.0
Previously Reported | Total CDMO
Error Corrections and Prior Period Adjustments Restatement [Line Items]
Cost of goods and services sold	52.1	63.1	78.8	75.6	67.9	114.3	146.6	46.7	269.6	375.5	132.0
Tax Adjustments
Error Corrections and Prior Period Adjustments Restatement [Line Items]
Net income (loss)	$ 11.2	$ (8.1)	$ 7.8	$ (1.4)					$ 9.5
Net income (loss) per common share
Basic (in dollars per share)	$ 0.22	$ (0.16)	$ 0.16	$ (0.03)					$ 0.19
Diluted (in dollars per share)	$ 0.22	$ (0.16)	$ 0.16	$ (0.03)					$ 0.19
Other Adjustments
Error Corrections and Prior Period Adjustments Restatement [Line Items]
Total revenues	$ (0.5)	$ (0.1)	$ (0.1)	$ (2.7)	9.7	(42.7)	(20.1)	34.0	$ (3.4)	(19.1)	21.9
Income (loss) from operations	9.8	(3.3)	(4.3)	0.5	9.4	(10.0)	(7.4)	(3.2)	2.7	(11.2)	4.7
Net income (loss)	$ 9.8	$ (3.3)	$ (4.3)	$ 0.5	$ 3.8	$ (7.7)	$ (5.1)	$ (2.4)	$ 2.7	$ (11.4)	$ 0.7
Net income (loss) per common share
Basic (in dollars per share)	$ 0.20	$ (0.07)	$ (0.09)	$ 0.01	$ 0.07	$ (0.14)	$ (0.10)	$ (0.05)	$ 0.06	$ (0.22)	$ 0.01
Diluted (in dollars per share)	$ 0.20	$ (0.07)	$ (0.09)	$ 0.01	$ 0.07	$ (0.14)	$ (0.10)	$ (0.05)	$ 0.06	$ (0.21)	$ 0.01
Other Adjustments | Product sales, net
Error Corrections and Prior Period Adjustments Restatement [Line Items]
Cost of goods and services sold	$ 0.5	$ (0.3)	$ 1.2	$ (0.9)	$ (0.9)	$ 1.1	$ 0.2	$ 0.2	$ 0.5	$ 0.6
Other Adjustments | Total CDMO
Error Corrections and Prior Period Adjustments Restatement [Line Items]
Cost of goods and services sold	$ 0.6	$ (1.1)	$ 1.0	$ (1.6)	$ 1.8	$ (36.8)	$ (12.7)	$ 37.7	$ (1.1)	$ (10.0)	$ 13.0

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