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Restatement of consolidated financial statements - Consolidated Statements of Operations (Details) - USD ($)
$ / shares in Units, shares in Millions, $ in Millions
 3 Months Ended 12 Months Ended
Dec. 31, 2022
Sep. 30, 2022
Jun. 30, 2022
Mar. 31, 2022
Dec. 31, 2021
Sep. 30, 2021
Jun. 30, 2021
Mar. 31, 2021
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Revenues:                      
Leases                 $ 4.9    
Total revenues $ 330.2 $ 239.9 $ 242.6 $ 304.8 $ 732.9 $ 286.3 $ 377.4 $ 377.0 1,117.5 $ 1,773.6 $ 1,577.3
Operating expenses:                      
Cost of goods and services sold                 693.1 748.1 537.0
Research and development                 188.3 235.2 237.9
Selling, general and administrative                 339.5 348.7 304.1
Goodwill impairment                 6.7 41.7 0.0
Amortization of intangible assets                 59.9 58.5 59.8
Total operating expenses                 1,287.5 1,432.2 1,138.8
Income (loss) from operations (55.3) (45.3) (76.3) 6.9 286.8 (44.7) 7.1 92.2 (170.0) 341.4 438.5
Other income (expense):                      
Interest expense                 (37.3) (34.5) (31.3)
Other, net                 (11.7) (3.7) 4.7
Total other income (expense), net                 (49.0) (38.2) (26.6)
Income (loss) before income taxes                 (219.0) 303.2 411.9
Income tax (benefit) provision                 (7.4) 83.7 106.1
Net income (loss) $ (67.0) $ (87.1) $ (52.9) $ (4.6) $ 193.1 $ (40.4) $ (0.5) $ 67.3 $ (211.6) $ 219.5 $ 305.8
Net income (loss) per common share                      
Basic (in dollars per share) $ (1.34) $ (1.75) $ (1.06) $ (0.09) $ 3.62 $ (0.75) $ (0.01) $ 1.26 $ (4.22) $ 4.10 $ 5.80
Diluted (in dollars per share) $ (1.34) $ (1.75) $ (1.06) $ (0.09) $ 3.60 $ (0.75) $ (0.01) $ 1.23 $ (4.22) $ 4.06 $ 5.68
Shares used in computing net income (loss) per common share                      
Basic (in shares)                 50.1 53.5 52.7
Diluted (in shares)                 50.1 54.1 53.8
Previously Reported                      
Revenues:                      
Total revenues $ 330.7 $ 240.0 $ 242.7 $ 307.5 $ 723.2 $ 329.0 $ 397.5 $ 343.0 $ 1,120.9 $ 1,792.7 $ 1,555.4
Operating expenses:                      
Research and development                 193.0 234.0 234.5
Selling, general and administrative                 340.3 348.4 303.3
Goodwill impairment                 6.7 41.7  
Amortization of intangible assets                 59.9 58.5 59.8
Total operating expenses                 1,293.6 1,440.1 1,121.6
Income (loss) from operations (65.1) (42.0) (72.0) 6.4 277.4 (34.7) 14.5 95.4 (172.7) 352.6 433.8
Other income (expense):                      
Interest expense                 (37.3) (34.5) (31.3)
Other, net                 (11.7) (3.7) 4.7
Total other income (expense), net                 (49.0) (38.2) (26.6)
Income (loss) before income taxes                 (221.7) 314.4 407.2
Income tax (benefit) provision                 2.1 83.5 102.1
Net income (loss) $ (88.0) $ (75.7) $ (56.4) $ (3.7) $ 189.3 $ (32.7) $ 4.6 $ 69.7 $ (223.8) $ 230.9 $ 305.1
Net income (loss) per common share                      
Basic (in dollars per share) $ (1.76) $ (1.52) $ (1.13) $ (0.07) $ 3.55 $ (0.61) $ 0.09 $ 1.31 $ (4.47) $ 4.32 $ 5.79
Diluted (in dollars per share) $ (1.76) $ (1.52) $ (1.13) $ (0.07) $ 3.53 $ (0.61) $ 0.09 $ 1.28 $ (4.47) $ 4.27 $ 5.67
Shares used in computing net income (loss) per common share                      
Basic (in shares)                 50.1 53.5 52.7
Diluted (in shares)                 50.1 54.1 53.8
Tax Adjustments                      
Other income (expense):                      
Income tax (benefit) provision                 $ (9.5)    
Net income (loss) $ 11.2 $ (8.1) $ 7.8 $ (1.4)         $ 9.5    
Net income (loss) per common share                      
Basic (in dollars per share) $ 0.22 $ (0.16) $ 0.16 $ (0.03)         $ 0.19    
Diluted (in dollars per share) $ 0.22 $ (0.16) $ 0.16 $ (0.03)         $ 0.19    
Other Adjustments                      
Revenues:                      
Total revenues $ (0.5) $ (0.1) $ (0.1) $ (2.7) $ 9.7 $ (42.7) $ (20.1) $ 34.0 $ (3.4) $ (19.1) $ 21.9
Operating expenses:                      
Research and development                 (4.7) 1.2 3.4
Selling, general and administrative                 (0.8) 0.3 0.8
Total operating expenses                 (6.1) (7.9) 17.2
Income (loss) from operations 9.8 (3.3) (4.3) 0.5 9.4 (10.0) (7.4) (3.2) 2.7 (11.2) 4.7
Other income (expense):                      
Income (loss) before income taxes                 2.7 (11.2) 4.7
Income tax (benefit) provision                   0.2 4.0
Net income (loss) $ 9.8 $ (3.3) $ (4.3) $ 0.5 $ 3.8 $ (7.7) $ (5.1) $ (2.4) $ 2.7 $ (11.4) $ 0.7
Net income (loss) per common share                      
Basic (in dollars per share) $ 0.20 $ (0.07) $ (0.09) $ 0.01 $ 0.07 $ (0.14) $ (0.10) $ (0.05) $ 0.06 $ (0.22) $ 0.01
Diluted (in dollars per share) $ 0.20 $ (0.07) $ (0.09) $ 0.01 $ 0.07 $ (0.14) $ (0.10) $ (0.05) $ 0.06 $ (0.21) $ 0.01
Product sales, net                      
Revenues:                      
Services                 $ 966.2 $ 1,023.9 $ 989.8
Operating expenses:                      
Cost of goods and services sold $ 167.8 $ 85.2 $ 92.2 $ 79.4 $ 144.1 $ 104.3 $ 81.4 $ 52.8 424.6 382.6 392.0
Product sales, net | Previously Reported                      
Revenues:                      
Services                 966.2 1,023.9 989.8
Operating expenses:                      
Cost of goods and services sold 167.3 85.5 91.0 80.3 145.0 103.2 81.2 52.6 424.1 382.0 392.0
Product sales, net | Other Adjustments                      
Operating expenses:                      
Cost of goods and services sold 0.5 (0.3) 1.2 (0.9) (0.9) 1.1 0.2 0.2 0.5 0.6  
Total CDMO                      
Revenues:                      
Total CDMO                 109.9 615.5 472.4
Operating expenses:                      
Cost of goods and services sold 52.7 62.0 79.8 74.0 69.7 77.5 133.9 84.4 268.5 365.5 145.0
Total CDMO | Previously Reported                      
Revenues:                      
Total CDMO                 113.3 634.6 450.5
Operating expenses:                      
Cost of goods and services sold 52.1 63.1 78.8 75.6 67.9 114.3 146.6 46.7 269.6 375.5 132.0
Total CDMO | Other Adjustments                      
Revenues:                      
Total CDMO                 (3.4) (19.1) 21.9
Operating expenses:                      
Cost of goods and services sold $ 0.6 $ (1.1) $ 1.0 $ (1.6) $ 1.8 $ (36.8) $ (12.7) $ 37.7 (1.1) (10.0) 13.0
Services                      
Revenues:                      
Services                 105.0 310.3 194.1
Services | Previously Reported                      
Revenues:                      
Services                 108.4 334.9 166.7
Services | Other Adjustments                      
Revenues:                      
Services                 (3.4) (24.6) 27.4
Leases                      
Revenues:                      
Leases                 4.9 305.2 278.3
Leases | Previously Reported                      
Revenues:                      
Leases                 4.9 299.7 283.8
Leases | Other Adjustments                      
Revenues:                      
Leases                   5.5 (5.5)
Contracts and grants                      
Revenues:                      
Services                 41.4 134.2 115.1
Contracts and grants | Previously Reported                      
Revenues:                      
Services                 $ 41.4 $ 134.2 $ 115.1