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Property, plant and equipment, net
 3 Months Ended
Mar. 31, 2023
Property Plant and Equipment Income Statement Disclosures [Abstract]  
Property, plant and equipment, net Property, plant and equipment, net
Property, plant and equipment, net consisted of the following:
March 31, 2023December 31, 2022
Land and improvements$31.9 $54.9 
Buildings, building improvements and leasehold improvements305.7 327.9 
Furniture and equipment515.5 567.5 
Software64.8 65.6 
Construction-in-progress174.1 185.5 
Property, plant and equipment, gross$1,092.0 $1,201.4 
Less: Accumulated depreciation & amortization(375.2)(383.8)
Total property, plant and equipment, net$716.8 $817.6 
As of March 31, 2023 and December 31, 2022, construction-in-progress primarily included costs incurred related to construction to advance the Company's CDMO capabilities.
Property, plant and equipment, net is stated at cost, less accumulated depreciation and amortization. During the year ended December 31, 2022, the Company recorded accelerated depreciation of $12.7 million reflecting a shortening of the useful life of certain property, plant and equipment which were to be used in the manufacturing process to fulfill the manufacturing services agreement with Janssen (the "Agreement"). For additional information related to the termination of the Agreement, refer to Note 13, "Revenue recognition".