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Stock-based compensation and stockholders' equity (Tables)
3 Months Ended
Mar. 31, 2023
Stockholders' Equity Note [Abstract]  
Share-based Payment Arrangement, Expensed and Capitalized, Amount
Stock-based compensation expense, net of forfeitures was recorded in the following financial statement line items:
Three Months Ended March 31,
20232022
Cost of product sales$1.4 $1.7 
Cost of CDMO0.3 0.4 
R&D0.7 1.1 
Selling, general and administrative4.4 6.7 
Total stock-based compensation expense$6.8 $9.9 
Schedule of Accumulated Other Comprehensive Income (Loss)
The following table includes changes in accumulated other comprehensive income (loss), net of tax by component:
Defined Benefit Pension PlanDerivative InstrumentsForeign Currency Translation AdjustmentsTotal
Balance at December 31, 2022
$3.5 $6.2 $(6.6)$3.1 
Other comprehensive loss before reclassifications— (4.4)(0.1)(4.5)
Amounts reclassified from accumulated other comprehensive income (loss)— 2.4 — 2.4 
Net current period other comprehensive loss— (2.0)(0.1)(2.1)
Balance at March 31, 2023
$3.5 $4.2 $(6.7)$1.0 
Balance at December 31, 2021
$(4.0)$(4.5)$(7.6)$(16.1)
Other comprehensive income before reclassifications— 4.9 0.5 5.4 
Amounts reclassified from accumulated other comprehensive income (loss)— 1.4 — 1.4 
Net current period other comprehensive income— 6.3 0.5 6.8 
Balance at March 31, 2022
$(4.0)$1.8 $(7.1)$(9.3)
Comprehensive Income (Loss)
The table below presents the tax effects related to each component of other comprehensive income (loss):
Three Months Ended March 31,
20232022
PretaxTax ExpenseNet of taxPretaxTax ExpenseNet of tax
Derivative instruments$(2.6)$0.6 $(2.0)$8.6 $(2.3)$6.3 
Foreign currency translation adjustments(0.1)— (0.1)0.7 (0.2)0.5 
Total adjustments$(2.7)$0.6 $(2.1)$9.3 $(2.5)$6.8