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Revenue recognition - Disaggregation of Revenue (Details) - USD ($) $ in Millions	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022
Disaggregation of Revenue [Line Items]
Total revenues	$ 165.1	$ 307.5
USG
Disaggregation of Revenue [Line Items]
Total revenues	31.0	112.5
Non-USG
Disaggregation of Revenue [Line Items]
Total revenues	134.1	195.0
Product sales, net
Disaggregation of Revenue [Line Items]
Revenue	143.4	237.1
Product sales, net | USG
Disaggregation of Revenue [Line Items]
Revenue	26.1	103.4
Product sales, net | Non-USG
Disaggregation of Revenue [Line Items]
Revenue	117.3	133.7
Contract Development And Manufacturing [Member]
Disaggregation of Revenue [Line Items]
Total CDMO	15.2	60.8
Contract Development And Manufacturing [Member] | USG
Disaggregation of Revenue [Line Items]
Total CDMO	0.0	0.0
Contract Development And Manufacturing [Member] | Non-USG
Disaggregation of Revenue [Line Items]
Total CDMO	15.2	60.8
Services
Disaggregation of Revenue [Line Items]
Revenue	13.4	51.8
Services | USG
Disaggregation of Revenue [Line Items]
Revenue	0.0	0.0
Services | Non-USG
Disaggregation of Revenue [Line Items]
Revenue	13.4	51.8
Leases
Disaggregation of Revenue [Line Items]
Leases	1.8	9.0
Leases | USG
Disaggregation of Revenue [Line Items]
Leases	0.0	0.0
Leases | Non-USG
Disaggregation of Revenue [Line Items]
Leases	1.8	9.0
Contracts and grants
Disaggregation of Revenue [Line Items]
Revenue	6.5	9.6
Contracts and grants | USG
Disaggregation of Revenue [Line Items]
Revenue	4.9	9.1
Contracts and grants | Non-USG
Disaggregation of Revenue [Line Items]
Revenue	$ 1.6	$ 0.5

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