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Stock-based compensation and stockholders' equity (Tables) | 6 Months Ended
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Jun. 30, 2023
Stockholders' Equity Note [Abstract] |
Share-based Payment Arrangement, Expensed and Capitalized, Amount | Stock-based compensation expense, net of forfeitures was recorded in the following financial statement line items:
| Three Months Ended June 30, |  | Six Months Ended June 30,
| 2023 |  | 2022 |  | 2023 |  | 2022
Cost of product sales | $ | 1.2 |  |  | $ | 1.9 |  |  | $ | 2.6 |  |  | $ | 3.6 |
Cost of CDMO | 0.3 |  |  | 0.6 |  |  | 0.6 |  |  | 1.0 |
R&D | 0.4 |  |  | 1.5 |  |  | 1.1 |  |  | 2.6 |
Selling, general and administrative | 6.4 |  |  | 8.3 |  |  | 10.8 |  |  | 15.0 |
Total stock-based compensation expense | $ | 8.3 |  |  | $ | 12.3 |  |  | $ | 15.1 |  |  | $ | 22.2 |
Schedule of Accumulated Other Comprehensive Income (Loss) | The following table includes changes in accumulated other comprehensive income (loss), net of tax by component:
|  | Defined Benefit Pension Plan |  | Derivative Instruments |  | Foreign Currency Translation Adjustments |  | Total
Balance at December 31, 2022 |  | $ | 3.5 |  |  | $ | 6.2 |  |  | $ | (6.6) |  |  | $ | 3.1 |
Other comprehensive income (loss) before reclassifications |  | — |  |  | (4.4) |  |  | (0.1) |  |  | (4.5) |
Amounts reclassified from accumulated other comprehensive income (loss) |  | — |  |  | 2.4 |  |  | — |  |  | 2.4 |
Net current period other comprehensive income (loss) |  | — |  |  | (2.0) |  |  | (0.1) |  |  | (2.1) |
Balance at March 31, 2023 |  | $ | 3.5 |  |  | $ | 4.2 |  |  | $ | (6.7) |  |  | $ | 1.0 |
Other comprehensive income (loss) before reclassifications |  | — |  |  | 1.2 |  |  | 2.6 |  |  | 3.8 |
Amounts reclassified from accumulated other comprehensive income (loss) |  | (3.5) |  |  | (2.9) |  |  | — |  |  | (6.4) |
Net current period other comprehensive income (loss) |  | (3.5) |  |  | (1.7) |  |  | 2.6 |  |  | (2.6) |
Balance at June 30, 2023 |  | $ | — |  |  | $ | 2.5 |  |  | $ | (4.1) |  |  | $ | (1.6) |
Balance at December 31, 2021 |  | $ | (4.0) |  |  | $ | (4.5) |  |  | $ | (7.6) |  |  | $ | (16.1) |
Other comprehensive income (loss) before reclassifications |  | — |  |  | 4.9 |  |  | 0.5 |  |  | 5.4 |
Amounts reclassified from accumulated other comprehensive income (loss) |  | — |  |  | 1.4 |  |  | — |  |  | 1.4 |
Net current period other comprehensive income (loss) |  | — |  |  | 6.3 |  |  | 0.5 |  |  | 6.8 |
Balance at March 31, 2022 |  | $ | (4.0) |  |  | $ | 1.8 |  |  | $ | (7.1) |  |  | $ | (9.3) |
Other comprehensive income (loss) before reclassifications |  | — |  |  | 1.9 |  |  | 0.4 |  |  | 2.3 |
Amounts reclassified from accumulated other comprehensive income (loss) |  | — |  |  | 0.9 |  |  | — |  |  | 0.9 |
Net current period other comprehensive income (loss) |  | — |  |  | 2.8 |  |  | 0.4 |  |  | 3.2 |
Balance at June 30, 2022 |  | $ | (4.0) |  |  | $ | 4.6 |  |  | $ | (6.7) |  |  | $ | (6.1) |
Comprehensive Income (Loss) | The tables below present the tax effects related to each component of other comprehensive income (loss):
| Three Months Ended June 30,
| 2023 |  | 2022
| Pretax |  | Tax Expense |  | Net of tax |  | Pretax |  | Tax Expense |  | Net of tax
Defined benefit pension plan | $ | (4.1) |  |  | $ | 0.6 |  |  | $ | (3.5) |  |  | $ | — |  |  | $ | — |  |  | $ | — |
Derivative instruments | (2.4) |  |  | 0.7 |  |  | (1.7) |  |  | 3.8 |  |  | (1.0) |  |  | 2.8 |
Foreign currency translation adjustments | 2.1 |  |  | 0.5 |  |  | 2.6 |  |  | 1.3 |  |  | (0.9) |  |  | 0.4 |
Total adjustments | $ | (4.4) |  |  | $ | 1.8 |  |  | $ | (2.6) |  |  | $ | 5.1 |  |  | $ | (1.9) |  |  | $ | 3.2 |
| Six Months Ended June 30,
| 2023 |  | 2022
| Pretax |  | Tax Expense |  | Net of tax |  | Pretax |  | Tax Expense |  | Net of tax
Defined benefit pension plan | $ | (4.1) |  |  | $ | 0.6 |  |  | $ | (3.5) |  |  | $ | — |  |  | $ | — |  |  | $ | — |
Derivative instruments | (5.0) |  |  | 1.3 |  |  | (3.7) |  |  | 12.4 |  |  | (3.3) |  |  | 9.1 |
Foreign currency translation adjustments | 2.0 |  |  | 0.5 |  |  | 2.5 |  |  | 2.0 |  |  | (1.1) |  |  | 0.9 |
Total adjustments | $ | (7.1) |  |  | $ | 2.4 |  |  | $ | (4.7) |  |  | $ | 14.4 |  |  | $ | (4.4) |  |  | $ | 10.0 |

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