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Stock-based compensation and stockholders' equity (Tables)
9 Months Ended
Sep. 30, 2023
Stockholders' Equity Note [Abstract]  
Schedule of Stock-based Compensation Expense
Stock-based compensation expense, net of forfeitures was recorded in the following financial statement line items:
Three Months Ended September 30,Nine Months Ended September 30,
2023202220232022
Cost of product sales$1.0 $1.8 $3.6 $5.4 
Cost of CDMO0.2 0.4 0.8 1.4 
R&D0.6 1.3 1.7 3.9 
Selling, general and administrative2.2 7.7 13.0 22.7 
Total stock-based compensation expense$4.0 $11.2 $19.1 $33.4 
Schedule of Accumulated Other Comprehensive Income (Loss)
The following table includes changes in accumulated other comprehensive income (loss), net of tax by component:
Defined Benefit Pension PlanDerivative InstrumentsForeign Currency
 Translation Adjustments
Total
Balance at December 31, 2022
$3.5 $6.2 $(6.6)$3.1 
Other comprehensive income (loss) before reclassifications— (4.4)(0.1)(4.5)
Amounts reclassified from accumulated other comprehensive income (loss)— 2.4 — 2.4 
Net current period other comprehensive income (loss)— (2.0)(0.1)(2.1)
Balance at March 31, 2023$3.5 $4.2 $(6.7)$1.0 
Other comprehensive income (loss) before reclassifications— 1.2 2.6 3.8 
Amounts reclassified from accumulated other comprehensive income (loss)(3.5)(2.9)— (6.4)
Net current period other comprehensive income (loss)(3.5)(1.7)2.6 (2.6)
Balance at June 30, 2023$— $2.5 $(4.1)$(1.6)
Other comprehensive income (loss) before reclassifications— 0.9 1.2 2.1 
Amounts reclassified from accumulated other comprehensive income (loss)— (3.1)— (3.1)
Net current period other comprehensive income (loss)— (2.2)1.2 (1.0)
Balance at September 30, 2023$— $0.3 $(2.9)$(2.6)
Balance at December 31, 2021
$(4.0)$(4.5)$(7.6)$(16.1)
Other comprehensive income (loss) before reclassifications— 4.9 0.5 5.4 
Amounts reclassified from accumulated other comprehensive income (loss)— 1.4 — 1.4 
Net current period other comprehensive income (loss)— 6.3 0.5 6.8 
Balance at March 31, 2022$(4.0)$1.8 $(7.1)$(9.3)
Other comprehensive income (loss) before reclassifications— 1.9 0.4 2.3 
Amounts reclassified from accumulated other comprehensive income (loss)— 0.9 — 0.9 
Net current period other comprehensive income (loss)— 2.8 0.4 3.2 
Balance at June 30, 2022$(4.0)$4.6 $(6.7)$(6.1)
Other comprehensive income (loss) before reclassifications— 2.6 (1.3)1.3 
Amounts reclassified from accumulated other comprehensive income (loss)— (0.4)— (0.4)
Net current period other comprehensive income (loss)— 2.2 (1.3)0.9 
Balance at September 30, 2022$(4.0)$6.8 $(8.0)$(5.2)
Schedule of Comprehensive Income (Loss)
The tables below present the tax effects related to each component of other comprehensive income (loss):
Three Months Ended September 30,
20232022
PretaxTax ExpenseNet of taxPretaxTax ExpenseNet of tax
Defined benefit pension plan$— $— $— $— $— $— 
Derivative instruments(3.1)0.9 (2.2)3.0 (0.8)2.2 
Foreign currency translation adjustments0.9 0.3 1.2 0.1 (1.4)(1.3)
Total adjustments$(2.2)$1.2 $(1.0)$3.1 $(2.2)$0.9 
Nine Months Ended September 30,
20232022
PretaxTax ExpenseNet of taxPretaxTax ExpenseNet of tax
Defined benefit pension plan$(4.1)$0.6 $(3.5)$— $— $— 
Derivative instruments(8.0)2.1 (5.9)15.4 (4.1)11.3 
Foreign currency translation adjustments2.9 0.8 3.7 2.1 (2.5)(0.4)
Total adjustments$(9.2)$3.5 $(5.7)$17.5 $(6.6)$10.9