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Adjustments to quarterly financial data - Statement of Operation (Details) - USD ($)
$ / shares in Units, shares in Millions, $ in Millions
 3 Months Ended 9 Months Ended
Sep. 30, 2023
Jun. 30, 2023
Mar. 31, 2023
Sep. 30, 2022
Jun. 30, 2022
Mar. 31, 2022
Sep. 30, 2023
Sep. 30, 2022
Revenues:                
Total revenues $ 270.5 $ 337.9 $ 164.3 $ 239.9 $ 242.6 $ 304.8 $ 772.7 $ 787.3
Operating expenses:                
Cost of goods and services sold 176.8     147.2     520.3 472.6
Research and development 15.3     42.2     82.0 141.3
Selling, general and administrative 86.0     81.8     278.7 246.1
Amortization of intangible assets 16.3     14.0     49.4 42.0
Total operating expenses 512.6     285.2     1,455.3 902.0
Loss from operations (242.1) (292.9) (147.6) (45.3) (76.3) 6.9 (682.6) (114.7)
Other income (expense):                
Interest expense (19.7)     (8.5)     (66.2) (24.5)
Other, net (3.4)     (13.4)     (2.1) (18.4)
Total other income (expense), net (23.8)     (21.9)     5.9 (42.9)
Loss before income taxes (265.9)     (67.2)     (676.7) (157.6)
Income tax provision (benefit) (2.5)     19.9     34.3 (13.0)
Net loss $ (263.4) $ (261.4) $ (186.2) $ (87.1) $ (52.9) $ (4.6) $ (711.0) $ (144.6)
Net loss per common share                
Basic (in dollars per share) $ (5.08) $ (5.16) $ (3.71) $ (1.75) $ (1.06) $ (0.09) $ (13.97) $ (2.88)
Diluted (in dollars per share) $ (5.08) $ (5.16) $ (3.71) $ (1.75) $ (1.06) $ (0.09) $ (13.97) $ (2.88)
Weighted average shares outstanding                
Basic (in shares) 51.8     49.9     50.9 50.2
Diluted (in shares) 51.8     49.9     50.9 50.2
Product sales, net                
Revenues:                
Services $ 249.8     $ 186.2     $ 695.4 $ 660.5
Operating expenses:                
Cost of goods and services sold 132.5 $ 134.9 $ 101.2 85.2 $ 92.2 $ 79.4 368.6 256.8
CDMO                
Revenues:                
Total CDMO revenues 14.2     36.3     57.7 92.5
Operating expenses:                
Cost of goods and services sold 44.3 55.7 51.7 62.0 79.8 74.0 151.7 215.8
Services                
Revenues:                
Services 13.2     36.1     52.2 87.8
Leases                
Revenues:                
Leases 1.0     0.2     5.5 4.7
Contracts and grants                
Revenues:                
Services $ 6.5     17.4     $ 19.6 34.3
Previously Reported                
Revenues:                
Total revenues   337.9 165.1 240.0 242.7 307.5   790.2
Operating expenses:                
Research and development       39.2       135.4
Selling, general and administrative       80.2       246.1
Amortization of intangible assets       14.0       42.0
Total operating expenses       282.0       897.8
Loss from operations   (292.9) (148.1) (42.0) (72.0) 6.4   (107.6)
Other income (expense):                
Interest expense       (8.5)       (24.5)
Other, net       (13.4)       (18.4)
Total other income (expense), net       (21.9)       (42.9)
Loss before income taxes       (63.9)       (150.5)
Income tax provision (benefit)       11.8       (14.7)
Net loss   $ (261.3) $ (183.0) $ (75.7) $ (56.4) $ (3.7)   $ (135.8)
Net loss per common share                
Basic (in dollars per share)   $ (5.15) $ (3.65) $ (1.52) $ (1.13) $ (0.07)   $ (2.71)
Diluted (in dollars per share)   $ (5.15) $ (3.65) $ (1.52) $ (1.13) $ (0.07)   $ (2.71)
Weighted average shares outstanding                
Basic (in shares)       49.9       50.2
Diluted (in shares)       49.9       50.2
Previously Reported | Product sales, net                
Revenues:                
Services       $ 186.2       $ 660.5
Operating expenses:                
Cost of goods and services sold   $ 134.9 $ 102.9 85.5 $ 91.0 $ 80.3   256.8
Previously Reported | CDMO                
Revenues:                
Total CDMO revenues       36.4       95.4
Operating expenses:                
Cost of goods and services sold   55.7 52.2 63.1 78.8 75.6   217.5
Previously Reported | Services                
Revenues:                
Services       36.2       90.7
Previously Reported | Leases                
Revenues:                
Leases       0.2       4.7
Previously Reported | Contracts and grants                
Revenues:                
Services       17.4       34.3
Tax Adjustments                
Other income (expense):                
Income tax provision (benefit)       8.1       1.7
Net loss   $ (0.1) $ (3.7) $ (8.1) $ 7.8 $ (1.4)   $ (1.7)
Net loss per common share                
Basic (in dollars per share)   $ (0.01) $ (0.07) $ (0.16) $ 0.16 $ (0.03)   $ (0.03)
Diluted (in dollars per share)   $ (0.01) $ (0.07) $ (0.16) $ 0.16 $ (0.03)   $ (0.03)
Other Adjustments                
Revenues:                
Total revenues     $ (0.8) $ (0.1) $ (0.1) $ (2.7)   $ (2.9)
Operating expenses:                
Research and development       3.0       5.9
Selling, general and administrative       1.6        
Total operating expenses       3.2       4.2
Loss from operations     0.5 (3.3) (4.3) 0.5   (7.1)
Other income (expense):                
Loss before income taxes       (3.3)       (7.1)
Net loss     $ 0.5 $ (3.3) $ (4.3) $ 0.5   $ (7.1)
Net loss per common share                
Basic (in dollars per share)     $ 0.01 $ (0.07) $ (0.09) $ 0.01   $ (0.14)
Diluted (in dollars per share)     $ 0.01 $ (0.07) $ (0.09) $ 0.01   $ (0.14)
Other Adjustments | Product sales, net                
Operating expenses:                
Cost of goods and services sold     $ (1.7) $ (0.3) $ 1.2 $ (0.9)    
Other Adjustments | CDMO                
Revenues:                
Total CDMO revenues       (0.1)       $ (2.9)
Operating expenses:                
Cost of goods and services sold     $ (0.5) (1.1) $ 1.0 $ (1.6)   (1.7)
Other Adjustments | Services                
Revenues:                
Services       $ (0.1)       $ (2.9)