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Property and Equipment (Details) - USD ($) $ in Thousands | Dec. 31, 2021 | Dec. 31, 2020
--- | --- | ---
Property and Equipment |  |
Cryogenic shippers and data loggers | $ 9,343 | $ 7,442
Freezers | 5,341 | 3,723
Furniture and fixtures | 2,204 | 2,727
Computers and software | 2,384 | 1,469
Machinery and equipment | 12,405 | 10,931
Trucks and autos | 497 | 437
Leasehold improvements | 21,657 | 4,599
Buildings | 5,808 | 5,359
Land | 806 | 790
Fixed assets in process | 8,583 | 8,070
Property, Plant and Equipment, Gross | 69,028 | 45,547
Less accumulated depreciation and amortization | (19,999) | (15,511)
Property, Plant and Equipment, Net, Total | $ 49,029 | $ 30,036

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- Definition Amount before accumulated depreciation of building structures held for productive use including addition, improvement, or renovation to the structure, including, but not limited to, interior masonry, interior flooring, electrical, and plumbing. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section 45 -Paragraph 4 -Subparagraph (f) -URI http://asc.fasb.org/extlink&oid=124098289&loc=d3e6812-107765 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 360 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=6391035&loc=d3e2868-110229 + Details
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