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Cash, Cash Equivalents and Short-Term Investments - Available-for-sale debt securities (Details) - USD ($)	Mar. 31, 2022	Dec. 31, 2021
Amortized Cost	$ 373,559,000	$ 383,547
Unrealized Gains		12
Unrealized Losses	(14,032,000)	(3,867)
Fair Value	359,527,000	379,692
U.S. Treasury notes
Amortized Cost	322,728,000	226,020
Unrealized Gains		12
Unrealized Losses	(5,789,000)	(2,136)
Fair Value	316,939,000	223,896
Corporate debt securities
Amortized Cost	50,831,000	157,527
Unrealized Losses	(8,243,000)	(1,731)
Fair Value	$ 42,588,000	$ 155,796

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- Definition

Amount, before tax, of unrealized gain in accumulated other comprehensive income (AOCI) on investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).

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