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Cash, Cash Equivalents and Short-Term Investments - Available-for-sale Investments (Details) - USD ($) $ in Thousands	Sep. 30, 2022	Dec. 31, 2021
Amortized Cost	$ 425,966	$ 383,547
Unrealized Gains	15	12
Unrealized Losses	(25,927)	(3,867)
Total, Fair Value	400,054	379,692
U.S. Treasury notes
Amortized Cost	211,391	226,020
Unrealized Gains	6	12
Unrealized Losses	(10,007)	(2,136)
Total, Fair Value	201,390	223,896
Corporate debt securities
Amortized Cost	214,575	157,527
Unrealized Gains	9
Unrealized Losses	(15,920)	(1,731)
Total, Fair Value	$ 198,664	$ 155,796

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Amount, before tax, of unrealized gain in accumulated other comprehensive income (AOCI) on investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).

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