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Consolidated Statements of Stockholders' Equity - USD ($)
Preferred Stock
Class A Preferred Stock
Private Placement
Preferred Stock
Class A Preferred Stock
Preferred Stock
Class B Preferred Stock
Private Placement
Preferred Stock
Class B Preferred Stock
Preferred Stock
Class C Preferred Stock
Common Stock
Private Placement
Common Stock
Additional Paid-In Capital
Private Placement
Additional Paid-In Capital
Accumulated Deficit
Private Placement
Accumulated Deficit
Accumulated Other Comprehensive Income
Private Placement
Accumulated Other Comprehensive Income
Private Placement
Total
Balance, Beginning at Dec. 31, 2019   $ 0   $ 0     $ 37,000   $ 285,609,000   $ (159,320,000)   $ (45,000)   $ 126,281,000
Balance, Beginning (in shares) at Dec. 31, 2019   0   0     37,339,787                
Net loss   $ 0   $ 0     $ 0   0   (32,693,000)   0   (32,693,000)
Other comprehensive loss, net of taxes   0   0     0   0   0   5,421,000   5,421,000
Stock-based compensation expense   0   0     0   8,833,000   0   0   8,833,000
Issuance of common stock for board of director compensation   $ 0   $ 0     $ 0   83,000   0   0   83,000
Issuance of common stock for board of director compensation (in shares)   0   0     2,869                
Issuance of common stock, net of costs $ 0   $ 0     $ 1,000   $ 28,159,000   $ 0   $ 0   $ 28,160,000  
Issuance of common stock, net of costs (in shares) 0   0     675,536                  
Issuance of Series C convertible preferred stock in private placement, net of costs of $7.7 million   $ 0   $ 0   $ 0 $ 0   237,225,000   0   0   237,225,000
Issuance of Series C convertible preferred stock in private placement, net of costs of $7.7 million (in shares)   0   0 250,000                    
Beneficial conversion feature of the Series C convertible preferred stock   $ 0   $ 0 $ (39,492,000)   0   39,492,000   0   0    
Deemed dividend on the Series C convertible preferred stock   0   0 39,492,000   0   (39,492,000)   0   0    
Paid-in-kind preferred stock dividend, including beneficial conversion feature   0   0 2,844,000   0   (2,844,000)   0   0    
Proceeds from exercise of stock options and warrants   $ 0   $ 0     $ 2,000   9,386,000   0   0   9,388,000
Proceeds from exercise of stock options and warrants (in shares)   0   0     1,818,866                
Paid-in-kind preferred stock dividend                             (2,844,000)
Balance, Ending at Dec. 31, 2020   $ 0   $ 0 $ 2,844,000   $ 40,000   566,451,000   (192,013,000)   5,376,000   382,698,000
Balance, Ending (in shares) at Dec. 31, 2020   0   0 250,000   39,837,058                
Net loss   $ 0   $ 0     $ 0   0   (275,528,000)   0   (275,528,000)
Other comprehensive loss, net of taxes   0   0     0   0   0   (6,619,000)   (6,619,000)
Stock-based compensation expense   0   0     0   15,334,000   0   0   15,334,000
Issuance of common stock for board of director compensation   $ 0   $ 0     $ 0   11,000   0   0   11,000
Issuance of common stock for board of director compensation (in shares)   0   0     229                
Issuance of common stock, net of costs   $ 0   $ 0     $ 4,000   269,821,000   0   0   269,825,000
Issuance of common stock, net of costs (in shares)   0   0     4,356,059                
Cost of Series C preferred stock conversion   $ 0   $ 0     $ 0   (1,800,000)   0   0   (1,800,000)
Issuance of common stock in direct placement, net   $ 0   $ 0     $ 3,000   248,908,000   0   0   248,911,000
Issuance of common stock in direct placement, net (in shares)   0   0     3,072,038                
Conversion of Series C preferred shares to common stock   $ 0   $ 0 $ (765,000)   $ 1,000   764,000   0   0    
Conversion of Series C preferred shares to common stock (in shares)   0   0 (50,000)   1,312,860                
Paid-in-kind preferred stock dividend, including beneficial conversion feature   $ 0   $ 0 $ 8,196,000   $ 0   (8,196,000)   0   0    
Paid-in-kind preferred stock dividend                             (8,196,000)
Proceeds from exercise of stock options   $ 0   $ 0     $ 2,000   8,994,000   0   0   8,996,000
Proceeds from exercise of stock options (in shares)   0   0     1,037,910                
Balance, Ending at Dec. 31, 2021   $ 0   $ 0 $ 10,275,000   $ 50,000   1,100,287,000   (467,541,000)   (1,243,000)   641,828,000
Balance, Ending (in shares) at Dec. 31, 2021   0   0 200,000   49,616,154                
Net loss   $ 0   $ 0     $ 0   0   (37,333,000)   0   (37,333,000)
Other comprehensive loss, net of taxes   0   0     0   0   0   (33,306,000)   (33,306,000)
Stock-based compensation expense   0   0     0   20,082,000   0   0   20,082,000
Paid-in-kind preferred stock dividend   0   0 $ 8,000,000   0   (8,000,000)   0   0   (8,000,000)
Issuance of common stock for Cell&Co acquisition   $ 0   $ 0     $ 0   479,000   0   0   479,000
Issuance of common stock for Cell&Co acquisition (in shares)   0   0     15,152                
Repurchase of common stock   $ 0   $ 0     $ (2,000)   0   (37,958,000)   0   $ (37,960,000)
Repurchase of common stock (in shares)   0   0     (1,604,994)               1,604,994
Vesting of restricted stock units   $ 0   $ 0     $ 0   0   0   0    
Vesting of restricted stock units (in shares)   0   0     101,070                
Proceeds from exercise of stock options   $ 0   $ 0     $ 0   2,048,000   0   0   $ 2,048,000
Proceeds from exercise of stock options (in shares)   0   0     206,898                
Balance, Ending at Dec. 31, 2022   $ 0   $ 0 $ 18,275,000   $ 48,000   $ 1,114,896,000   $ (542,832,000)   $ (34,549,000)   $ 555,838,000
Balance, Ending (in shares) at Dec. 31, 2022   0   0 200,000   48,334,280