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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Cash Flows From Operating Activities:      
Net loss $ (37,333) $ (275,528) $ (32,693)
Adjustments to reconcile net loss to net cash provided by (used in) operating activities:      
Loss on extinguishment of debt   251,754 0
Depreciation and amortization 22,765 20,247 9,869
Amortization of debt discount 2,581 1,236 437
Unrealized (gain) loss on investments in equity securities 11,406 1,386 (845)
Realized loss on investments in equity securities   0 1,090
Realized (gain) loss on available-for-sale debt securities 102 81 32
Stock-based compensation expense 20,082 15,345 8,916
Loss on disposal of property and equipment 800 542 384
Excess and obsolete inventory 651 0 0
Gain on insurance settlement (4,815) 0 0
Insurance proceeds for operations 9,883 0 0
Provision for bad debt 234 26 197
Change in contingent consideration 216 0 0
Changes in operating assets and liabilities, net of effects of acquisition:      
Accounts receivable (4,137) (7,270) (2,617)
Inventories (14,204) (5,979) 1,322
Prepaid expenses and other current assets (1,598) 3,056 (7,520)
Deposits (60) 211 (152)
Change in operating lease right-of-use assets and lease liabilities 569 562 134
Accounts payable and other accrued expenses (6,483) (398) 4,245
Accrued compensation and related expenses (1,569) 2,522 3,143
Deferred revenue (530) 102 (309)
Net deferred tax (asset) liability (411) 231 (499)
Net cash provided by (used in) operating activities (1,851) 8,126 (14,866)
Cash Flows From Investing Activities:      
Purchases of property and equipment (22,107) (23,882) (8,918)
Insurance proceeds for loss of fixed assets 3,000 0 0
Purchases of short-term investments (163,788) (482,707) (158,736)
Sales/maturities of short-term investments 131,858 44,000 149,233
Patent and trademark costs (614) (255) (200)
Software development costs (1,476) (870) (551)
Cash paid for acquisitions 6,554 5,540 363,140
Net cash used in investing activities (59,681) (469,254) (382,312)
Cash Flows From Financing Activities:      
Proceeds from exercise of stock options and warrants 2,048 8,995 9,388
Repurchase of common stock (37,960) 0 0
Proceeds from issuance of Series C convertible preferred stock, net of issuance costs   248,911 237,225
Proceeds from issuance of common stock, net of issuance costs   0 28,160
Proceeds from public offering, net of offering costs   269,825 0
Repayment of finance lease liabilities (82) (60) (70)
Repayment of note payable (3,180) (3,397) 0
Proceeds from issuance of convertible senior notes   40,068 115,000
Payment of deferred financing costs   0 (4,118)
Net cash provided by (used in) financing activities (39,174) 564,342 385,585
Effect of exchange rate changes on cash and cash equivalents (1,800) (986) 1,231
Net change in cash and cash equivalents (102,506) 102,228 (10,362)
Cash and cash equivalents - beginning of year 139,101 36,873 47,235
Cash and cash equivalents - end of year 36,595 139,101 36,873
Supplemental Disclosure of Cash Flow Information:      
Cash paid for interest 3,628 3,297 1,823
Cash paid for income taxes 1,979 1,315 60
Supplemental Disclosure of Non-Cash Investing and Financing Activities:      
Net unrealized gain (loss) on available-for-sale debt securities 23,439 3,958 161
Reclassification of realized gain on available-for-sale debt securities to earnings 46 27 3
Fixed assets included in accounts payable and accrued liabilities 1,003 1,412 499
Purchase of equipment through finance lease obligations   0 205
Paid-in-kind preferred stock dividend, including beneficial conversion feature $ 8,000 8,196 2,844
Common stock issued for conversion of debt and accrued interest   $ 765 $ 0