<SEC-DOCUMENT>0001558370-25-011126.txt : 20250812
<SEC-HEADER>0001558370-25-011126.hdr.sgml : 20250812
<ACCEPTANCE-DATETIME>20250811215430
ACCESSION NUMBER:		0001558370-25-011126
CONFORMED SUBMISSION TYPE:	NT 10-Q
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20250630
FILED AS OF DATE:		20250812
DATE AS OF CHANGE:		20250811
EFFECTIVENESS DATE:		20250812

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Cryoport, Inc.
		CENTRAL INDEX KEY:			0001124524
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				880313393
		STATE OF INCORPORATION:			NV
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		NT 10-Q
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-34632
		FILM NUMBER:		251203832

	BUSINESS ADDRESS:	
		STREET 1:		112 WESTWOOD PLACE, SUITE 350
		CITY:			BRENTWOOD
		STATE:			TN
		ZIP:			37027
		BUSINESS PHONE:		(949) 232-1900

	MAIL ADDRESS:	
		STREET 1:		112 WESTWOOD PLACE, SUITE 350
		CITY:			BRENTWOOD
		STATE:			TN
		ZIP:			37027

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CRYOPORT SYSTEMS LLC
		DATE OF NAME CHANGE:	20010614

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CRYOPORT SYSTEMS INC
		DATE OF NAME CHANGE:	20000923
</SEC-HEADER>
<DOCUMENT>
<TYPE>NT 10-Q
<SEQUENCE>1
<FILENAME>cyrx-20250630xnt10q.htm
<DESCRIPTION>NT 10-Q
<TEXT>
<!--Enhanced HTML document created with Toppan Merrill Bridge  11.0.0.141--><!--Created on: 8/12/2025 01:44:10 AM (UTC)--><html><head><meta charset="UTF-8"><title>Form 12b-25</title></head><body><div style="margin-top:30pt;"></div><div style="max-width:100%;padding-left:10.35%;padding-right:10.35%;position:relative;"><div style="clear:both;max-width:100%;position:relative;"><div><table style="border-collapse:collapse;font-size:16pt;height:max-content;margin-left:auto;margin-right:auto;width:100%;" align="center"><tr style="height:1pt;"><td style="vertical-align:top;width:71.39%;margin:0pt;padding:0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="position:absolute;top:0pt;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:1pt;visibility:hidden;">&#8203;</font></p></div></div></td><td colspan="2" style="vertical-align:top;width:28.6%;margin:0pt;padding:0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="position:absolute;top:0pt;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:1pt;visibility:hidden;">&#8203;</font></p></div></div></td></tr><tr><td style="vertical-align:top;width:71.39%;margin:0pt;padding:1.45pt 0pt 0pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:12pt;font-weight:bold;text-align:center;margin:0pt 0pt 0pt 72pt;"><font style="margin-left:0pt;visibility:hidden;">&#8203;</font></p></td><td colspan="2" style="vertical-align:top;width:28.6%;margin:0pt;padding:1.45pt 5.75pt 0pt 5.75pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:12pt;font-weight:bold;text-align:center;margin:0pt;"><font style="font-size:9pt;font-weight:normal;visibility:hidden;">&#8203;</font></p></td></tr><tr><td style="vertical-align:top;width:71.39%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt 0pt 0pt 72pt;"><b style="font-size:12pt;font-weight:bold;">UNITED</b><b style="font-size:12pt;font-weight:bold;letter-spacing:-0.15pt;"> </b><b style="font-size:12pt;font-weight:bold;letter-spacing:-0.1pt;">STATES</b></p></td><td style="vertical-align:top;width:13.98%;margin:0pt;padding:0pt 5.75pt 0pt 5.75pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:9pt;visibility:hidden;">&#8203;</font></p></td><td style="vertical-align:top;width:14.61%;margin:0pt;padding:0pt 5.75pt 0pt 5.75pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;padding-left:64.8pt;text-align:right;text-indent:-64.8pt;margin:0pt;"><font style="font-size:9pt;visibility:hidden;">&#8203;</font></p></td></tr><tr><td style="vertical-align:top;width:71.39%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt 0pt 0pt 72pt;"><b style="font-size:12pt;font-weight:bold;">SECURITIES</b><b style="font-size:12pt;font-weight:bold;letter-spacing:-0.2pt;"> </b><b style="font-size:12pt;font-weight:bold;">AND</b><b style="font-size:12pt;font-weight:bold;letter-spacing:-0.25pt;"> </b><b style="font-size:12pt;font-weight:bold;">EXCHANGE</b><b style="font-size:12pt;font-weight:bold;letter-spacing:-0.15pt;"> </b><b style="font-size:12pt;font-weight:bold;letter-spacing:-0.1pt;">COMMISSION</b></p></td><td style="vertical-align:top;width:13.98%;margin:0pt;padding:0pt 5.75pt 0pt 5.75pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:9pt;visibility:hidden;">&#8203;</font></p></td><td style="vertical-align:top;width:14.61%;margin:0pt;padding:0pt 5.75pt 0pt 5.75pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:right;margin:0pt;"><font style="font-size:9pt;visibility:hidden;">&#8203;</font></p></td></tr><tr><td style="vertical-align:top;width:71.39%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt 0pt 0pt 72pt;"><b style="font-size:12pt;font-weight:bold;">Washington,</b><b style="font-size:12pt;font-weight:bold;letter-spacing:-0.75pt;"> </b><b style="font-size:12pt;font-weight:bold;">D.C.</b><b style="font-size:12pt;font-weight:bold;letter-spacing:-0.75pt;"> </b><b style="font-size:12pt;font-weight:bold;">20549</b></p></td><td colspan="2" style="vertical-align:top;width:28.6%;border-bottom:1px solid #000000;margin:0pt;padding:0pt 5.75pt 0pt 5.75pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:9pt;visibility:hidden;">&#8203;</font></p></td></tr><tr><td style="vertical-align:top;width:71.39%;border-right:1px solid #000000;margin:0pt;padding:1.45pt 0pt 0pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt 0pt 0pt 72pt;"><font style="font-size:12pt;font-weight:bold;margin-left:0pt;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt 0pt 0pt 72pt;"><b style="font-size:12pt;font-weight:bold;">FORM 12b-25</b></p></td><td colspan="2" style="vertical-align:top;width:28.6%;border-bottom:1px solid #000000;border-left:1px solid #000000;border-right:1px solid #000000;border-top:1px solid #000000;margin:0pt;padding:1.45pt 5.5pt 0pt 5.5pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:9pt;text-align:center;margin:0pt;">SEC<font style="letter-spacing:-0.3pt;"> </font>FILE<font style="letter-spacing:-0.2pt;"> </font><font style="letter-spacing:-0.1pt;">NUMBER</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:9pt;text-align:center;margin:0pt;"><b style="font-weight:bold;">001-34632</b></p></td></tr><tr><td style="vertical-align:top;width:71.39%;border-right:1px solid #000000;margin:0pt;padding:1.45pt 0pt 0pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:12pt;font-weight:bold;text-align:center;margin:0pt 0pt 0pt 72pt;">NOTIFICATION<b style="font-weight:bold;letter-spacing:-0.2pt;"> </b>OF<b style="font-weight:bold;letter-spacing:-0.15pt;"> </b>LATE<b style="font-weight:bold;letter-spacing:-0.1pt;"> FILING</b></p></td><td colspan="2" style="vertical-align:top;width:28.6%;border-bottom:1px solid #000000;border-left:1px solid #000000;border-right:1px solid #000000;border-top:1px solid #000000;margin:0pt;padding:1.45pt 5.5pt 0pt 5.5pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:9pt;font-weight:bold;text-align:center;margin:0pt;"><font style="font-weight:normal;">CUSIP</font><font style="font-weight:normal;letter-spacing:-0.4pt;"> </font><font style="font-weight:normal;letter-spacing:-0.1pt;">NUMBER</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:9pt;font-weight:bold;text-align:center;margin:0pt;">229050307</p></td></tr></table></div><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:8pt;visibility:hidden;">&#8203;</font></p><div style="padding-left:10.8pt;" align="left"><table style="border-collapse:collapse;font-size:16pt;height:max-content;padding-left:0pt;padding-right:0pt;table-layout:auto;width:95%;"><tr style="height:1pt;"><td style="vertical-align:top;width:19.99%;margin:0pt;padding:0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="position:absolute;top:0pt;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:1pt;visibility:hidden;">&#8203;</font></p></div></div></td><td style="vertical-align:top;width:19.99%;margin:0pt;padding:0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="position:absolute;top:0pt;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:1pt;visibility:hidden;">&#8203;</font></p></div></div></td><td style="vertical-align:top;width:19.99%;margin:0pt;padding:0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="position:absolute;top:0pt;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:1pt;visibility:hidden;">&#8203;</font></p></div></div></td><td style="vertical-align:top;width:19.99%;margin:0pt;padding:0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="position:absolute;top:0pt;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:1pt;visibility:hidden;">&#8203;</font></p></div></div></td><td style="vertical-align:top;width:20%;margin:0pt;padding:0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="position:absolute;top:0pt;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:1pt;visibility:hidden;">&#8203;</font></p></div></div></td></tr><tr style="height:1pt;"><td style="vertical-align:top;width:19.99%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:2pt 0pt 2pt 0pt;"><i style="font-size:11.5pt;font-style:italic;">(Check</i><i style="font-size:11.5pt;font-style:italic;letter-spacing:-0.2pt;"> </i><i style="font-size:11.5pt;font-style:italic;letter-spacing:-0.1pt;">one):</i></p></td><td style="vertical-align:top;width:19.99%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:2pt 0pt 2pt 0pt;"><font style="font-family:'Times New Roman';font-size:11.5pt;">&#9723;</font><font style="font-size:11.5pt;">&#160;&#160;Form</font><font style="font-size:11.5pt;letter-spacing:-0.2pt;"> </font><font style="font-size:11.5pt;">10-</font><font style="font-size:11.5pt;letter-spacing:-0.5pt;">K</font></p></td><td style="vertical-align:top;width:19.99%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:2pt 0pt 2pt 0pt;"><font style="font-family:'Times New Roman';font-size:11.5pt;">&#9723;</font><font style="font-size:11.5pt;">&#160;&#160;Form</font><font style="font-size:11.5pt;letter-spacing:-0.1pt;"> </font><font style="font-size:11.5pt;">20-</font><font style="font-size:11.5pt;letter-spacing:-0.5pt;">F</font></p></td><td style="vertical-align:top;width:19.99%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:2pt 0pt 2pt 0pt;"><font style="font-family:'Times New Roman';font-size:11.5pt;">&#9723;</font><font style="font-size:11.5pt;">&#160;&#160;Form</font><font style="font-size:11.5pt;letter-spacing:-0.2pt;"> </font><font style="font-size:11.5pt;">11-</font><font style="font-size:11.5pt;letter-spacing:-0.5pt;">K</font></p></td><td style="vertical-align:top;width:20%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:2pt 0pt 2pt 0pt;"><font style="font-size:11.5pt;visibility:hidden;">&#8203;</font></p></td></tr><tr style="height:1pt;"><td style="vertical-align:top;width:19.99%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:2pt 0pt 2pt 0pt;"><font style="font-size:11.5pt;visibility:hidden;">&#8203;</font></p></td><td style="vertical-align:top;width:19.99%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:2pt 0pt 2pt 0pt;"><font style="font-family:'Times New Roman';font-size:11.5pt;">&#8999;</font><font style="font-size:11.5pt;">&#160;&#160;Form</font><font style="font-size:11.5pt;letter-spacing:-0.2pt;"> </font><font style="font-size:11.5pt;">10-</font><font style="font-size:11.5pt;letter-spacing:-0.5pt;">Q</font></p></td><td style="vertical-align:top;width:19.99%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:2pt 0pt 2pt 0pt;"><font style="font-family:'Times New Roman';font-size:11.5pt;">&#9723;</font><font style="font-size:11.5pt;">&#160;&#160;Form</font><font style="font-size:11.5pt;letter-spacing:-0.2pt;"> </font><font style="font-size:11.5pt;">10-</font><font style="font-size:11.5pt;letter-spacing:-0.5pt;">D</font></p></td><td style="vertical-align:top;width:19.99%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:2pt 0pt 2pt 0pt;"><font style="font-family:'Times New Roman';font-size:11.5pt;">&#9723;</font><font style="font-size:11.5pt;">&#160;&#160;Form</font><font style="font-size:11.5pt;letter-spacing:-0.25pt;"> </font><font style="font-size:11.5pt;">N-</font><font style="font-size:11.5pt;letter-spacing:-0.25pt;">CEN</font></p></td><td style="vertical-align:top;width:20%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:2pt 0pt 2pt 0pt;"><font style="font-family:'Times New Roman';font-size:11.5pt;">&#9723;</font><font style="font-size:11.5pt;">&#160;&#160;Form</font><font style="font-size:11.5pt;letter-spacing:-0.25pt;"> </font><font style="font-size:11.5pt;">N-</font><font style="font-size:11.5pt;letter-spacing:-0.25pt;">CSR</font></p></td></tr></table></div><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:8pt;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt 0pt 0pt 100.8pt;"><font style="font-size:11.5pt;">For Period Ended: </font><u style="font-size:11.5pt;text-decoration-color:#000000;text-decoration-line:underline;text-decoration-style:solid;">June 30, 2025</u></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:3pt 0pt 0pt 100.8pt;"><font style="font-size:12pt;margin-left:0pt;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:3pt 0pt 0pt 100.8pt;"><font style="font-family:'Times New Roman';font-size:12pt;">&#9723;</font><font style="font-size:12pt;">&#160;&#160;&#160;&#160;Transition</font><font style="font-size:12pt;letter-spacing:-0.2pt;"> </font><font style="font-size:12pt;">Report</font><font style="font-size:12pt;letter-spacing:-0.1pt;"> </font><font style="font-size:12pt;">on</font><font style="font-size:12pt;letter-spacing:-0.1pt;"> </font><font style="font-size:12pt;">Form</font><font style="font-size:12pt;letter-spacing:-0.1pt;"> </font><font style="font-size:12pt;">10-</font><font style="font-size:12pt;letter-spacing:-0.5pt;">K</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:3pt 0pt 0pt 100.8pt;"><font style="font-family:'Times New Roman';font-size:12pt;">&#9723;</font><font style="font-size:12pt;">&#160;&#160;&#160;&#160;Transition</font><font style="font-size:12pt;letter-spacing:-0.2pt;"> </font><font style="font-size:12pt;">Report</font><font style="font-size:12pt;letter-spacing:-0.1pt;"> </font><font style="font-size:12pt;">on</font><font style="font-size:12pt;letter-spacing:-0.1pt;"> </font><font style="font-size:12pt;">Form</font><font style="font-size:12pt;letter-spacing:-0.1pt;"> </font><font style="font-size:12pt;">20-</font><font style="font-size:12pt;letter-spacing:-0.5pt;">F</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:3pt 0pt 0pt 100.8pt;"><font style="font-family:'Times New Roman';font-size:12pt;">&#9723;</font><font style="font-size:12pt;">&#160;&#160;&#160;&#160;Transition</font><font style="font-size:12pt;letter-spacing:-0.2pt;"> </font><font style="font-size:12pt;">Report</font><font style="font-size:12pt;letter-spacing:-0.1pt;"> </font><font style="font-size:12pt;">on</font><font style="font-size:12pt;letter-spacing:-0.1pt;"> </font><font style="font-size:12pt;">Form</font><font style="font-size:12pt;letter-spacing:-0.1pt;"> </font><font style="font-size:12pt;">11-</font><font style="font-size:12pt;letter-spacing:-0.5pt;">K</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:3pt 0pt 0pt 100.8pt;"><font style="font-family:'Times New Roman';font-size:12pt;">&#9723;</font><font style="font-size:12pt;">&#160;&#160;&#160;&#160;Transition</font><font style="font-size:12pt;letter-spacing:-0.2pt;"> </font><font style="font-size:12pt;">Report</font><font style="font-size:12pt;letter-spacing:-0.1pt;"> </font><font style="font-size:12pt;">on</font><font style="font-size:12pt;letter-spacing:-0.1pt;"> </font><font style="font-size:12pt;">Form</font><font style="font-size:12pt;letter-spacing:-0.1pt;"> </font><font style="font-size:12pt;">10-</font><font style="font-size:12pt;letter-spacing:-0.5pt;">Q</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:4.05pt 0pt 0pt 101pt;"><font style="font-size:12pt;">For the Transition Period Ended: </font><u 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#000000;margin:0pt;padding:0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="position:absolute;top:50%;transform:translate(0,-50%);width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:1pt;visibility:hidden;">&#8203;</font></p></div></div></td></tr><tr style="height:1pt;"><td style="vertical-align:middle;width:100%;border-bottom:1.0pt solid #000000;border-left:1.0pt solid #000000;border-right:1.0pt solid #000000;border-top:1.0pt solid #000000;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:8pt 0pt 8pt 0pt;"><i style="font-size:12pt;font-style:italic;">Read</i><i style="font-size:12pt;font-style:italic;letter-spacing:-0.2pt;"> </i><i style="font-size:12pt;font-style:italic;">Instruction</i><i style="font-size:12pt;font-style:italic;letter-spacing:-0.05pt;"> </i><i style="font-size:12pt;font-style:italic;">(on</i><i style="font-size:12pt;font-style:italic;letter-spacing:-0.1pt;"> </i><i style="font-size:12pt;font-style:italic;">back</i><i style="font-size:12pt;font-style:italic;letter-spacing:-0.1pt;"> </i><i style="font-size:12pt;font-style:italic;">page)</i><i style="font-size:12pt;font-style:italic;letter-spacing:-0.15pt;"> </i><i style="font-size:12pt;font-style:italic;">Before</i><i style="font-size:12pt;font-style:italic;letter-spacing:-0.1pt;"> </i><i style="font-size:12pt;font-style:italic;">Preparing</i><i style="font-size:12pt;font-style:italic;letter-spacing:-0.1pt;"> </i><i style="font-size:12pt;font-style:italic;">Form.</i><i style="font-size:12pt;font-style:italic;letter-spacing:-0.05pt;"> </i><i style="font-size:12pt;font-style:italic;">Please</i><i style="font-size:12pt;font-style:italic;letter-spacing:-0.15pt;"> </i><i style="font-size:12pt;font-style:italic;">Print</i><i style="font-size:12pt;font-style:italic;letter-spacing:-0.05pt;"> </i><i style="font-size:12pt;font-style:italic;">or</i><i style="font-size:12pt;font-style:italic;letter-spacing:-0.05pt;"> </i><i style="font-size:12pt;font-style:italic;letter-spacing:-0.1pt;">Type.</i><i style="font-size:12pt;font-style:italic;letter-spacing:-0.1pt;"><br></i><b style="font-size:12pt;font-weight:bold;">Nothing</b><b style="font-size:12pt;font-weight:bold;letter-spacing:-0.15pt;"> </b><b style="font-size:12pt;font-weight:bold;">in</b><b style="font-size:12pt;font-weight:bold;letter-spacing:-0.15pt;"> </b><b style="font-size:12pt;font-weight:bold;">this</b><b style="font-size:12pt;font-weight:bold;letter-spacing:-0.15pt;"> </b><b style="font-size:12pt;font-weight:bold;">Form</b><b style="font-size:12pt;font-weight:bold;letter-spacing:-0.1pt;"> </b><b style="font-size:12pt;font-weight:bold;">shall</b><b style="font-size:12pt;font-weight:bold;letter-spacing:-0.15pt;"> </b><b style="font-size:12pt;font-weight:bold;">be</b><b style="font-size:12pt;font-weight:bold;letter-spacing:-0.2pt;"> </b><b style="font-size:12pt;font-weight:bold;">construed</b><b style="font-size:12pt;font-weight:bold;letter-spacing:-0.15pt;"> </b><b style="font-size:12pt;font-weight:bold;">to</b><b style="font-size:12pt;font-weight:bold;letter-spacing:-0.15pt;"> </b><b style="font-size:12pt;font-weight:bold;">imply</b><b style="font-size:12pt;font-weight:bold;letter-spacing:-0.15pt;"> </b><b style="font-size:12pt;font-weight:bold;">that</b><b style="font-size:12pt;font-weight:bold;letter-spacing:-0.2pt;"> </b><b style="font-size:12pt;font-weight:bold;">the</b><b style="font-size:12pt;font-weight:bold;letter-spacing:-0.2pt;"> </b><b style="font-size:12pt;font-weight:bold;">Commission</b><b style="font-size:12pt;font-weight:bold;letter-spacing:-0.25pt;"> </b><b style="font-size:12pt;font-weight:bold;">has</b><b style="font-size:12pt;font-weight:bold;letter-spacing:-0.15pt;"> </b><b style="font-size:12pt;font-weight:bold;">verified</b><b style="font-size:12pt;font-weight:bold;letter-spacing:-0.15pt;"> </b><b style="font-size:12pt;font-weight:bold;">any information contained herein.</b></p></td></tr></table></div><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:8pt;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:12pt;margin:0pt 54pt 0pt 10.8pt;">If<font style="letter-spacing:-0.2pt;"> </font>the<font style="letter-spacing:-0.2pt;"> </font>notification<font style="letter-spacing:-0.15pt;"> </font>relates<font style="letter-spacing:-0.05pt;"> </font>to<font style="letter-spacing:-0.15pt;"> </font>a<font style="letter-spacing:-0.2pt;"> </font>portion<font style="letter-spacing:-0.15pt;"> </font>of<font style="letter-spacing:-0.2pt;"> </font>the<font style="letter-spacing:-0.2pt;"> </font>filing<font style="letter-spacing:-0.15pt;"> </font>checked<font style="letter-spacing:-0.15pt;"> </font>above,<font style="letter-spacing:-0.15pt;"> </font>identify<font style="letter-spacing:-0.15pt;"> </font>the<font style="letter-spacing:-0.1pt;"> </font>Item(s)<font style="letter-spacing:-0.2pt;"> </font>to<font style="letter-spacing:-0.15pt;"> </font>which the notification relates:</p><p style="font-family:'Times New Roman','Times','serif';font-size:12pt;padding-bottom:1pt;border-bottom:1.0pt solid #000000;margin:5.8pt 0pt 0pt 10.8pt;"><font style="font-size:8pt;margin-left:0pt;margin-top:12pt;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;font-weight:bold;margin:12.64pt 0pt 0pt 10.8pt;"><b style="font-size:11.5pt;font-weight:bold;">PART</b><b style="font-size:11.5pt;font-weight:bold;letter-spacing:-0.1pt;"> </b><b style="font-size:11.5pt;font-weight:bold;">I</b><b style="font-size:11.5pt;font-weight:bold;letter-spacing:-0.1pt;"> </b><b style="font-size:11.5pt;font-weight:bold;">&#8212;</b><b style="font-size:11.5pt;font-weight:bold;letter-spacing:-0.1pt;"> </b><b style="font-size:11.5pt;font-weight:bold;">REGISTRANT</b><b style="font-size:11.5pt;font-weight:bold;letter-spacing:-0.05pt;"> </b><b style="font-size:11.5pt;font-weight:bold;letter-spacing:-0.1pt;">INFORMATION</b></p><p style="font-family:'Times New Roman','Times','serif';font-size:12pt;margin:0pt 0pt 0pt 10.8pt;"><font style="font-size:8pt;font-weight:bold;margin-left:0pt;margin-top:12pt;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;padding-bottom:1pt;border-bottom:1.0pt solid #000000;margin:0.34pt 0pt 0pt 10.8pt;"><b style="font-size:11.5pt;font-weight:bold;">CRYOPORT, INC.</b></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:4.59pt 0pt 0pt 10.8pt;"><font style="font-size:11.5pt;">Full</font><font style="font-size:11.5pt;letter-spacing:-0.1pt;"> </font><font style="font-size:11.5pt;">Name</font><font style="font-size:11.5pt;letter-spacing:-0.1pt;"> </font><font style="font-size:11.5pt;">of</font><font style="font-size:11.5pt;letter-spacing:-0.1pt;"> Registrant</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:12pt;margin:0pt 0pt 0pt 10.8pt;"><font style="font-size:8pt;margin-left:0pt;margin-top:12pt;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:12pt;padding-bottom:1pt;border-bottom:1.0pt solid #000000;margin:0.34pt 0pt 0pt 10.8pt;"><font style="font-size:8pt;margin-left:0pt;margin-top:12pt;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:4.59pt 0pt 0pt 10.8pt;"><font style="font-size:11.5pt;">Former</font><font style="font-size:11.5pt;letter-spacing:-0.1pt;"> </font><font style="font-size:11.5pt;">Name</font><font style="font-size:11.5pt;letter-spacing:-0.1pt;"> </font><font style="font-size:11.5pt;">if</font><font style="font-size:11.5pt;letter-spacing:-0.05pt;"> </font><font style="font-size:11.5pt;letter-spacing:-0.1pt;">Applicable</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:12pt;margin:0pt 0pt 0pt 10.8pt;"><font style="font-size:8pt;margin-left:0pt;margin-top:12pt;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;padding-bottom:1pt;border-bottom:1.0pt solid #000000;margin:0pt 0pt 0pt 10.8pt;"><b style="font-size:11.5pt;font-weight:bold;">112 Westwood Place, Suite 350</b></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:4.59pt 0pt 0pt 10.8pt;"><font style="font-size:11.5pt;">Address</font><font style="font-size:11.5pt;letter-spacing:-0.2pt;"> </font><font style="font-size:11.5pt;">of</font><font style="font-size:11.5pt;letter-spacing:-0.1pt;"> </font><font style="font-size:11.5pt;">Principal</font><font style="font-size:11.5pt;letter-spacing:-0.1pt;"> </font><font style="font-size:11.5pt;">Executive</font><font style="font-size:11.5pt;letter-spacing:-0.1pt;"> </font><font style="font-size:11.5pt;">Office</font><font style="font-size:11.5pt;letter-spacing:-0.15pt;"> </font><font style="font-size:11.5pt;">(Street</font><font style="font-size:11.5pt;letter-spacing:-0.05pt;"> </font><font style="font-size:11.5pt;">and</font><font style="font-size:11.5pt;letter-spacing:0.05pt;"> </font><font style="font-size:11.5pt;letter-spacing:-0.1pt;">Number)</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:12pt;margin:0pt 0pt 0pt 10.8pt;"><font style="font-size:8pt;margin-left:0pt;margin-top:12pt;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;padding-bottom:1pt;border-bottom:1.0pt solid #000000;margin:0pt 0pt 0pt 10.8pt;"><b style="font-size:11.5pt;font-weight:bold;">Brentwood, TN 37027</b></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:4.59pt 0pt 0pt 10.8pt;"><font style="font-size:11.5pt;">City,</font><font style="font-size:11.5pt;letter-spacing:-0.05pt;"> </font><font style="font-size:11.5pt;">State</font><font style="font-size:11.5pt;letter-spacing:-0.1pt;"> </font><font style="font-size:11.5pt;">and</font><font style="font-size:11.5pt;letter-spacing:-0.05pt;"> </font><font style="font-size:11.5pt;">Zip </font><font style="font-size:11.5pt;letter-spacing:-0.2pt;">Code</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:12pt;margin:0pt 0pt 0pt 10.8pt;"><font style="font-size:8pt;margin-left:0pt;margin-top:12pt;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:12pt;margin:0pt 0pt 0pt 10.8pt;"><font style="font-size:8pt;margin-left:0pt;margin-top:12pt;visibility:hidden;">&#8203;</font></p><div style="padding-left:10.8pt;" align="left"><table style="border-collapse:collapse;font-size:16pt;height:max-content;width:97%;"><tr style="height:1pt;"><td style="vertical-align:top;width:20.24%;margin:0pt;padding:0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="position:absolute;top:0pt;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:1pt;visibility:hidden;">&#8203;</font></p></div></div></td><td style="vertical-align:top;width:79.75%;margin:0pt;padding:0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="position:absolute;top:0pt;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:1pt;visibility:hidden;">&#8203;</font></p></div></div></td></tr><tr><td style="vertical-align:top;width:20.24%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;">SEC 1344 (01-19)</p></td><td style="vertical-align:top;width:79.75%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;">Potential<font style="letter-spacing:-0.05pt;"> </font>persons<font style="letter-spacing:-0.1pt;"> </font>who<font style="letter-spacing:-0.25pt;"> </font>are<font style="letter-spacing:-0.2pt;"> </font>to<font style="letter-spacing:-0.1pt;"> </font>respond<font style="letter-spacing:-0.25pt;"> </font>to<font style="letter-spacing:-0.1pt;"> </font>the<font style="letter-spacing:-0.1pt;"> </font>collection<font style="letter-spacing:-0.35pt;"> </font>of<font style="letter-spacing:-0.05pt;"> </font>information<font style="letter-spacing:-0.1pt;"> </font>contained<font style="letter-spacing:-0.1pt;"> </font>in this Form are not required to respond unless the Form displays a currently valid OMB control number.</p></td></tr></table></div><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:7pt;visibility:hidden;">&#8203;</font></p></div><div style="clear:both;margin-bottom:30pt;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:12pt 0pt 0pt 0pt;"><font style="visibility:hidden;">&#8203;</font></p></div></div><hr style="background-color:#000000;clear:both;color:#000000;height:2pt;line-height:0;margin-bottom:30pt;margin-left:10.35%;margin-right:10.35%;margin-top:30pt;page-break-after:always;width:79.3%;border-width:0;"><div style="max-width:100%;padding-left:10.35%;padding-right:10.35%;position:relative;"><div style="clear:both;max-width:100%;position:relative;"><div style="padding-left:10.8pt;" align="left"><table style="border-collapse:collapse;font-size:16pt;height:max-content;width:97.1%;"><tr style="height:1pt;"><td style="vertical-align:top;width:39.72%;margin:0pt;padding:0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="position:absolute;top:0pt;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:1pt;visibility:hidden;">&#8203;</font></p></div></div></td><td style="vertical-align:top;width:23.27%;margin:0pt;padding:0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="position:absolute;top:0pt;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:1pt;visibility:hidden;">&#8203;</font></p></div></div></td><td style="vertical-align:top;width:36.99%;margin:0pt;padding:0pt 5.4pt 0pt 5.4pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="position:absolute;top:0pt;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:1pt;visibility:hidden;">&#8203;</font></p></div></div></td></tr><tr><td style="vertical-align:top;width:39.72%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:9pt;margin:0pt;">Board<font style="letter-spacing:-0.1pt;"> </font>of<font style="letter-spacing:-0.05pt;"> </font>Governors<font style="letter-spacing:-0.1pt;"> </font>of<font style="letter-spacing:-0.05pt;"> </font>the<font style="letter-spacing:-0.05pt;"> </font>Federal<font style="letter-spacing:-0.05pt;"> </font>Reserve<font style="letter-spacing:-0.05pt;"> </font><font style="letter-spacing:-0.1pt;">System</font></p></td><td style="vertical-align:top;width:23.27%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:9pt;text-align:center;margin:0pt;">OMB<font style="letter-spacing:-0.1pt;"> </font>Number 7100-<font style="letter-spacing:-0.2pt;">0091</font></p></td><td style="vertical-align:top;width:36.99%;margin:0pt;padding:0pt 5.4pt 0pt 5.4pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:9pt;text-align:center;margin:0pt;">Approval<font style="letter-spacing:-0.2pt;"> </font>expires<font style="letter-spacing:-0.1pt;"> </font>February<font style="letter-spacing:-0.1pt;"> </font>28,<font style="letter-spacing:-0.05pt;"> </font><font style="letter-spacing:-0.2pt;">2026</font></p></td></tr></table></div><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:7pt;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt 0pt 12pt 10.8pt;"><b style="font-weight:bold;">PART II &#8212; RULES 12b-25(b) AND (c)</b></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt 0pt 12pt 10.8pt;">If the subject report could not be filed without unreasonable effort or expense and the registrant seeks relief pursuant to Rule 12b-25(b), the following should be completed. (Check box if appropriate)</p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt 0pt 0pt 10.8pt;"><font style="font-size:4pt;margin-left:0pt;visibility:hidden;">&#8203;</font></p><div style="padding-left:10.8pt;" align="left"><table style="border-collapse:collapse;font-size:16pt;height:max-content;width:97%;"><tr><td style="vertical-align:middle;width:4.93%;border-right:1px solid #000000;margin:0pt;padding:5.75pt 0pt 5.75pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;line-height:12pt;margin:0pt 10.8pt 0pt 0pt;"><font style="font-family:'Times New Roman';font-size:11.5pt;">&#8999;</font></p></td><td style="vertical-align:top;width:95.06%;border-left:1px solid #000000;margin:0pt;padding:5.75pt 0pt 5.75pt 0pt;"><div border="0" cellpadding="0" cellspacing="0" style="border-collapse:collapse;display:table;font-family:'Times New Roman','Times','serif';font-size:11pt;line-height:12pt;margin-bottom:0pt;margin-top:0pt;table-layout:fixed;width:100%;border:0pt;"><div style="display:table-row;"><div style="width:3.6pt;display:table-cell;"></div><div style="display:table-cell;font-family:'Times New Roman','Times','serif';font-size:11pt;vertical-align:text-top;white-space:nowrap;width:18pt;padding:0pt;">(a)</div><div style="display:table-cell;padding:0pt;"><font style="font-family:'Times New Roman','Times','serif';font-size:11pt;font-style:normal;font-weight:normal;">The reason described in reasonable detail in Part III of this Form could not be eliminated without unreasonable effort or expense;</font></div></div></div><div style="margin-top:6pt;"></div><div border="0" cellpadding="0" cellspacing="0" style="display:table;"><div style="display:table-row;"><div style="display:table-cell;width:3.6pt;padding:0pt;"></div><div style="display:table-cell;vertical-align:text-top;white-space:nowrap;width:18pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;line-height:12pt;margin-bottom:6pt;margin-top:0pt;">(b)</p></div><div style="display:table-cell;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;line-height:12pt;margin-bottom:6pt;margin-top:0pt;">The subject annual report, semi-annual report, transition report on Form 10-K, Form 20-F, Form 11-K, Form N-CEN or Form N-CSR, or portion thereof, will be filed on or before the fifteenth calendar day following the prescribed due date; or the subject quarterly report or transition report on Form 10-Q or subject distribution report on Form 10-D, or portion thereof, will be filed on or before the fifth calendar day following the prescribed due date; and</p></div></div></div><div border="0" cellpadding="0" cellspacing="0" style="display:table;"><div style="display:table-row;"><div style="display:table-cell;width:3.6pt;padding:0pt;"></div><div style="display:table-cell;vertical-align:text-top;white-space:nowrap;width:18pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;line-height:12pt;margin-bottom:1.2pt;margin-top:0pt;">(c)</p></div><div style="display:table-cell;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;line-height:12pt;margin-bottom:1.2pt;margin-top:0pt;">The accountant&#8217;s statement or other exhibit required by Rule 12b-25(c) has been attached if applicable.</p></div></div></div></td></tr></table></div><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt 0pt 12pt 10.8pt;"><b style="font-weight:bold;">PART III &#8212; NARRATIVE</b></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt 0pt 12pt 10.8pt;">State below in reasonable detail why Forms 10-K, 20-F, 11-K, 10-Q, 10-D, N-CEN, N-CSR, or the transition report or portion thereof, could not be filed within the prescribed time period.</p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt 0pt 12pt 10.8pt;"><font style="background:#ffffff;">The Registrant is unable to file the subject report in a timely manner because the Registrant was not able to timely compile the subject report without unreasonable effort or expense. The Registrant fully expects to be able to file within the additional time allowed by this report.</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt 0pt 12pt 10.8pt;"><b style="font-weight:bold;">PART IV &#8212; OTHER INFORMATION</b></p><table border="0" cellpadding="0" cellspacing="0"><tr><td style="width:10.8pt;padding:0pt;"></td><td style="vertical-align:text-top;white-space:nowrap;width:26.65pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin-bottom:0pt;margin-top:0pt;">(1)</p></td><td style="padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin-bottom:0pt;margin-top:0pt;">Name and telephone number of person to contact in regard to this notification</p></td></tr></table><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;padding-left:26.95pt;text-indent:-26.95pt;margin:0pt 0pt 0pt 11pt;"><font style="margin-left:0pt;visibility:hidden;">&#8203;</font></p><div style="padding-left:10.8pt;" align="left"><table style="border-collapse:collapse;font-size:16pt;height:max-content;padding-left:0pt;padding-right:0pt;width:97%;"><tr style="height:1pt;"><td style="vertical-align:bottom;width:49.69%;margin:0pt;padding:0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="bottom:0pt;position:absolute;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:1pt;visibility:hidden;">&#8203;</font></p></div></div></td><td style="vertical-align:top;width:4.14%;margin:0pt;padding:0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="position:absolute;top:0pt;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:1pt;visibility:hidden;">&#8203;</font></p></div></div></td><td style="vertical-align:bottom;width:15.37%;margin:0pt;padding:0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="bottom:0pt;position:absolute;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:1pt;visibility:hidden;">&#8203;</font></p></div></div></td><td style="vertical-align:top;width:3.55%;margin:0pt;padding:0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="position:absolute;top:0pt;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:1pt;visibility:hidden;">&#8203;</font></p></div></div></td><td style="vertical-align:bottom;width:27.22%;margin:0pt;padding:0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="bottom:0pt;position:absolute;width:100%;"><p style="font-family:'Times New 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If answer is no, identify report(s</font>).&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="font-family:'Times New Roman';font-size:11.5pt;">&#8999;</font>&#160;Yes&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="font-family:'Segoe UI Symbol';">&#9744;</font><font style="font-family:'Segoe UI Symbol';">&#160;</font>No</p></td></tr></table><table border="0" cellpadding="0" cellspacing="0"><tr><td style="width:11pt;padding:0pt;"></td><td style="vertical-align:text-top;white-space:nowrap;width:26.9pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin-bottom:10pt;margin-top:0pt;">(3)</p></td><td style="padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin-bottom:10pt;margin-top:0pt;">Is it anticipated that any significant change in results of operations from the corresponding period for the last fiscal year will be reflected by the earnings statements to be included in the subject report or portion thereof?&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="font-family:'Times New Roman';font-size:11.5pt;">&#8999;</font><font style="font-family:'Segoe UI Symbol';">&#160;</font>Yes&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="font-family:'Segoe UI Symbol';">&#9744;</font><font style="font-family:'Segoe UI Symbol';">&#160;</font>No</p></td></tr></table><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt 0pt 10pt 38pt;">If so, attach an explanation of the anticipated change, both narratively and quantitatively, and, if appropriate, state the reasons why a reasonable estimate of the results cannot be made.</p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;">On August 5, 2025, the Registrant issued a press release announcing financial results for the quarter ended June 30, 2025, and included a copy of such press release as an exhibit to the Registrant&#8217;s Current Report on Form 8-K furnished by the Registrant with the Securities and Exchange Commission on August 6, 2025. Information about the Registrant&#8217;s financial results for the quarter ended June 30, 2025 compared to the three months ended June 30, 2024 was included in such press release.</p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p></div><div style="clear:both;margin-bottom:30pt;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:12pt 0pt 0pt 0pt;"><font style="visibility:hidden;">&#8203;</font></p></div></div><hr style="background-color:#000000;clear:both;color:#000000;height:2pt;line-height:0;margin-bottom:30pt;margin-left:10.35%;margin-right:10.35%;margin-top:30pt;page-break-after:always;width:79.3%;border-width:0;"><div style="max-width:100%;padding-left:10.35%;padding-right:10.35%;position:relative;"><div style="clear:both;max-width:100%;position:relative;"><div style="padding-left:10.8pt;" align="left"><table style="border-collapse:collapse;font-size:16pt;height:max-content;width:97%;"><tr style="height:1pt;"><td style="vertical-align:top;width:25.86%;margin:0pt;padding:0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="position:absolute;top:0pt;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:1pt;visibility:hidden;">&#8203;</font></p></div></div></td><td style="vertical-align:top;width:48.42%;margin:0pt;padding:0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="position:absolute;top:0pt;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:1pt;visibility:hidden;">&#8203;</font></p></div></div></td><td style="vertical-align:top;width:25.71%;margin:0pt;padding:0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="position:absolute;top:0pt;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:1pt;visibility:hidden;">&#8203;</font></p></div></div></td></tr><tr><td style="vertical-align:top;width:25.86%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p></td><td style="vertical-align:top;width:48.42%;border-bottom:1.0pt solid #000000;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;">CRYOPORT, INC.</p></td><td style="vertical-align:top;width:25.71%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p></td></tr><tr><td style="vertical-align:top;width:25.86%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p></td><td style="vertical-align:top;width:48.42%;border-top:1.0pt solid #000000;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;">(Name of Registrant as Specified in Charter)</p></td><td style="vertical-align:top;width:25.71%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p></td></tr></table></div><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt 0pt 6pt 11pt;">has caused this notification to be signed on its behalf by the undersigned hereunto duly authorized.</p><div style="padding-left:10.8pt;" align="left"><table style="border-collapse:collapse;font-size:16pt;height:max-content;padding-left:0pt;padding-right:0pt;width:97%;"><tr style="height:1pt;"><td style="vertical-align:bottom;width:8.34%;margin:0pt;padding:0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="bottom:0pt;position:absolute;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:1pt;visibility:hidden;">&#8203;</font></p></div></div></td><td style="vertical-align:bottom;width:42.66%;margin:0pt;padding:0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="bottom:0pt;position:absolute;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:1pt;visibility:hidden;">&#8203;</font></p></div></div></td><td style="vertical-align:bottom;width:2.79%;margin:0pt;padding:0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="bottom:0pt;position:absolute;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:1pt;visibility:hidden;">&#8203;</font></p></div></div></td><td style="vertical-align:bottom;width:3.69%;margin:0pt;padding:0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="bottom:0pt;position:absolute;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:1pt;visibility:hidden;">&#8203;</font></p></div></div></td><td style="vertical-align:bottom;width:42.49%;margin:0pt;padding:0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="bottom:0pt;position:absolute;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:1pt;visibility:hidden;">&#8203;</font></p></div></div></td></tr><tr><td style="vertical-align:bottom;width:8.34%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;">Date</p></td><td style="vertical-align:bottom;width:42.66%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;">August 12, 2025</p></td><td style="vertical-align:bottom;width:2.79%;border-bottom:1px solid transparent;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;">&#160;&#160;&#160;&#160;</p></td><td style="vertical-align:bottom;width:3.69%;border-bottom:1px solid transparent;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;">By</p></td><td 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