    <SEC-DOCUMENT>0001341004-18-000252-index.html : 20180427
    <SEC-HEADER>0001341004-18-000252.hdr.sgml : 20180427
    <ACCEPTANCE-DATETIME>20180427163245
    ACCESSION NUMBER:		0001341004-18-000252
    CONFORMED SUBMISSION TYPE:	486BPOS
    PUBLIC DOCUMENT COUNT:		10
    FILED AS OF DATE:		20180427
    DATE AS OF CHANGE:		20180427
    EFFECTIVENESS DATE:		20180427

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			BlackRock Health Sciences Trust
    		CENTRAL INDEX KEY:			0001314966
    		IRS NUMBER:				000000000
    		STATE OF INCORPORATION:			DE

    	FILING VALUES:
    		FORM TYPE:		486BPOS
    		SEC ACT:		1933 Act
    		SEC FILE NUMBER:	333-210770
    		FILM NUMBER:		18784498

    	BUSINESS ADDRESS:
    		STREET 1:		100 BELLEVUE PARKWAY
    		CITY:			WILMINGTON
    		STATE:			DE
    		ZIP:			19809
    		BUSINESS PHONE:		(888) 825-2257

    	MAIL ADDRESS:
    		STREET 1:		100 BELLEVUE PARKWAY
    		CITY:			WILMINGTON
    		STATE:			DE
    		ZIP:			19809

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			BlackRock Health Sciences Trust
    		CENTRAL INDEX KEY:			0001314966
    		IRS NUMBER:				000000000
    		STATE OF INCORPORATION:			DE

    	FILING VALUES:
    		FORM TYPE:		486BPOS
    		SEC ACT:		1940 Act
    		SEC FILE NUMBER:	811-21702
    		FILM NUMBER:		18784499

    	BUSINESS ADDRESS:
    		STREET 1:		100 BELLEVUE PARKWAY
    		CITY:			WILMINGTON
    		STATE:			DE
    		ZIP:			19809
    		BUSINESS PHONE:		(888) 825-2257

    	MAIL ADDRESS:
    		STREET 1:		100 BELLEVUE PARKWAY
    		CITY:			WILMINGTON
    		STATE:			DE
    		ZIP:			19809
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>486BPOS
    <SEQUENCE>1
    <FILENAME>bme_486b.htm
    <DESCRIPTION>486BPOS
    <TEXT>
    Document 1 - file: bme_486b.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.2G ADVSR CONTR
    <SEQUENCE>2
    <FILENAME>exg2.htm
    <DESCRIPTION>EXHIBIT (G)(2) - CLOSED-END FUND MASTER ADVISORY FEE WAIVER AGREEMENT
    <TEXT>
    Document 2 - file: exg2.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.2H DISTR CONTR
    <SEQUENCE>3
    <FILENAME>exh2.htm
    <DESCRIPTION>EXHIBIT (H)(2) - SECOND AMENDED AND RESTATED DISTRIBUTION AGREEMENT
    <TEXT>
    Document 3 - file: exh2.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.2H DISTR CONTR
    <SEQUENCE>4
    <FILENAME>exh4.htm
    <DESCRIPTION>EXHIBIT (H)(4) - AMENDMENT TO THE SUB-PLACEMENT AGENT AGREEMENT
    <TEXT>
    Document 4 - file: exh4.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.2N OTH CONSENT
    <SEQUENCE>5
    <FILENAME>exn.htm
    <DESCRIPTION>EXHIBIT (N) - CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM FOR THE REGISTRANT
    <TEXT>
    Document 5 - file: exn.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-1
    <SEQUENCE>6
    <FILENAME>exs3.htm
    <DESCRIPTION>EXHIBIT (S)(3)
    <TEXT>
    Document 6 - file: exs3.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>image00001.jpg
    <TEXT>
    Document 7 - file: image00001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>image1.jpg
    <TEXT>
    Document 8 - file: image1.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>image2.jpg
    <TEXT>
    Document 9 - file: image2.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>image3.jpg
    <TEXT>
    Document 10 - file: image3.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>