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Consolidated Statements of Operations - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Income Statement [Abstract]    
Revenue $ 0 $ 0
Operating expenses:    
Research and development 21,577 23,243
General and administrative 8,530 8,266
Impairment of intangible asset 200 310
Total operating expenses 30,307 31,819
Loss from operations (30,307) (31,819)
Other income (expense):    
Interest expense, net (60) (133)
Other expense, net (248) (72)
Warrant expense (3,100) (11)
Change in fair value of warrant liability 17,507  
Total other income (expense), net 14,099 (205)
Net loss (16,208) (32,024)
Loss attributable to common stockholders-basic (13,863) (32,024)
Loss attributable to common stockholders-diluted $ (31,370) $ (32,024)
Loss per common share-basic $ (0.97) $ (2.42)
Loss per common share-diluted $ (2.18) $ (2.42)
Weighted-average shares used to compute loss per common share-basic 14,256,954 13,231,126
Weighted-average shares used to compute loss per common share-diluted 14,389,192 13,231,126