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Property and Equipment - Schedule of Property and Equipment (Detail) - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015
Property, Plant and Equipment [Line Items]
Total property and equipment	$ 13,247	$ 13,202
Less: accumulated depreciation	(9,387)	(7,989)
Property and equipment, net	3,860	5,213
Office Equipment [Member]
Property, Plant and Equipment [Line Items]
Total property and equipment	266	539
Laboratory Equipment [Member]
Property, Plant and Equipment [Line Items]
Total property and equipment	4,443	4,337
Leasehold Improvements [Member]
Property, Plant and Equipment [Line Items]
Total property and equipment	7,683	7,683
Construction in Progress [Member]
Property, Plant and Equipment [Line Items]
Total property and equipment	759	547
Software [Member]
Property, Plant and Equipment [Line Items]
Total property and equipment	$ 96	$ 96

X

- Definition

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
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- Definition

Amount before accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

+ References

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+ References

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