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Stock-Based Compensation - Summary of Stock Option Activity Under the 2012 and 2013 Plans (Detail) - USD ($)
$ / shares in Units, $ in Thousands
 12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]    
Number of Options, Outstanding Beginning Balance 1,229,339  
Number of Options, Granted 464,240  
Number of Options, Exercised (3,685)  
Number of Options, Cancelled (112,878)  
Number of Options, Outstanding Ending Balance 1,577,016 1,229,339
Number of Options, Vested and expected to vest outstanding 1,492,341  
Number of Options, Exercisable 561,693  
Weighted Average Exercise Price, Outstanding Beginning Balance $ 7.32  
Weighted Average Exercise Price, Granted 2.02  
Weighted Average Exercise Price, Exercised 0.76  
Weighted Average Exercise Price, Cancelled 4.97  
Weighted Average Exercise Price, Outstanding Ending Balance 5.95 $ 7.32
Weighted Average Exercise Price, Vested and expected to vest outstanding 5.97  
Weighted Average Exercise Price, Exercisable $ 6.79  
Weighted Average Remaining Contractual Term, Outstanding 8 years 4 months 24 days 9 years
Weighted Average Remaining Contractual Term, Vested and expected to vest outstanding 8 years 4 months 24 days  
Weighted Average Remaining Contractual Term, Exercisable 7 years 9 months 18 days  
Aggregate Intrinsic Value, Outstanding $ 71 $ 4,679
Aggregate Intrinsic Value, Vested and expected to vest outstanding 69  
Aggregate Intrinsic Value, Exercisable $ 52