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Income Taxes - Schedule of Reconciliation of Income Tax Expense (Benefit) Computed at Statutory Federal Income Tax Rate (Detail)	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015
Income Tax Disclosure [Abstract]
Federal income tax (benefit) at statutory rate	34.00%	34.00%
(Increase) decrease income tax benefit resulting from:
Permanent differences	29.00%	(1.20%)
Net Operating Loss Limitation	(111.10%)
R&D Credit Limitation	(1.50%)
Change in valuation allowance	48.70%	(31.70%)
Other	0.90%	(1.20%)
Income tax expense (benefit)	0.00%	0.00%

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Effective income tax rate reconciliation net operating loss limitation.

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Effective Income Tax Rate Reconciliation Permanent Differences

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Effective income tax rate reconciliation R and D credit limitation.

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Percentage of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 740
-SubTopic 10
-Section 50
-Paragraph 13
-URI http://asc.fasb.org/extlink&oid=65882285&loc=d3e32698-109319

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-Name Accounting Standards Codification
-Topic 235
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-Section S99
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Percentage of domestic federal statutory tax rate applicable to pretax income (loss).

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Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to changes in the valuation allowance for deferred tax assets.

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Reference 1: http://www.xbrl.org/2003/role/presentationRef
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Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to other adjustments.

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