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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
CASH FLOWS FROM OPERATING ACTIVITIES:    
Net loss $ (16,208) $ (32,024)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation 1,673 1,614
Deferred rent and lease incentive (533) (322)
Impairment of intangible asset 200 310
Stock-based compensation 1,548 1,228
Change in fair value of warrant (17,507)  
Warrant expense in connection with private placement 3,100 11
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets 148 475
Accrued expenses due to Intrexon Corporation 1,494 1,539
Accounts payable (435) (2,844)
Accounts payable due to Intrexon Corporation 131 211
Accrued expenses 653 (232)
Net cash used in operating activities (25,736) (30,034)
CASH FLOWS FROM INVESTING ACTIVITIES:    
Purchases of property and equipment (320) (1,949)
Net cash used in investing activities (320) (1,949)
CASH FLOWS FROM FINANCING ACTIVITIES:    
Proceeds from issuance of common stock, preferred stock, and warrants in connection with private placement, net of issuance costs 27,630  
Proceeds from overallotment, net of issuance costs of $377   4,738
Repayments on equipment term loan (583) (406)
Proceeds from exercise of stock options 2 39
Net cash provided by financing activities 27,049 4,371
Net increase (decrease) in cash and cash equivalents 993 (27,612)
Cash and cash equivalents-Beginning of period 30,915 58,527
Cash and cash equivalents-End of period 31,908 30,915
Supplemental Disclosure of Non-Cash Items:    
Fair market value of private placement warrants at issuance 30,704  
Supplemental Disclosure of Cash Flow information:    
Cash paid for taxes 257 79
Cash paid for interest $ 66 $ 94