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Stock-Based Compensation (Tables) | 3 Months Ended
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Mar. 31, 2019
Disclosure of Compensation Related Costs, Share-based Payments [Abstract] |
Summary of Stock Option Activity Under the 2012 and 2013 Plans | Stock option activity under the Company’s 2012 Equity Incentive Plan (the “2012 Plan”) and 2013 Equity Incentive Plan (the “2013 Plan”) for the three months ended March 31, 2019 is summarized as follows:
|  | Number of Options |  |  | Weighted- Average Exercise Price |  |  | Weighted- Average Remaining Contractual Term (in years) |  |  | Aggregate Intrinsic Value (in thousands) |
Outstanding at December 31, 2018 |  |  | 3,339,471 |  |  | $ | 1.03 |  |  |  | 8.1 |  |  | $ | — |
Cancelled |  |  | (1,536,304 | ) |  |  | 0.57 |  |  |  | — |  |  |  | — |
Outstanding at March 31, 2019 |  |  | 1,803,167 |  |  | $ | 1.03 |  |  |  | 7.2 |  |  | $ | — |
Vested and expected to vest at March 31, 2019 |  |  | 1,766,323 |  |  | $ | 1.41 |  |  |  | 7.2 |  |  | $ | — |
Exercisable at March 31, 2019 |  |  | 1,723,797 |  |  | $ | 1.37 |  |  |  | 7.1 |  |  | $ | — |
Summary of Stock-Based Compensation and Resricted stock awards | The allocation of stock-based compensation for all options granted and restricted stock awards is as follows:
|  | Three Months Ended March 31, |
|  | 2019 |  |  | 2018 |
|  | (in thousands) |
Research and development |  | $ | (38 | ) |  | $ | 96 |
General and administrative |  |  | 145 |  |  |  | 307 |
Total stock-based compensation expense |  | $ | 107 |  |  | $ | 403 |
Summary of Weighted-Average Assumptions Used in the Black-Scholes Option Pricing Model to Determine the Fair Value of the Employee Stock Option Grants | The weighted-average assumptions used in the Black-Scholes option pricing model to determine the fair value of the employee stock option grants and non-employee stock options grants for the three months ended March 31, 2018 were as follows:
|  | Three Months Ended March 31, 2018 |
|  | Employees |  |  | Non-employees |
Risk-free interest rate |  |  | 2.70 | % |  |  | 1.97 | %
Expected volatility |  |  | 88.2 | % |  |  | 74.0 | %
Expected term (in years) |  |  | 6.08 |  |  |  | 6.08 |
Expected dividend yield |  |  | 0.0 | % |  |  | 0.0 | %

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- Definition Tabular disclosure of the allocation of equity-based compensation costs to a given line item on the balance sheet and income statement for the period. This may include the reporting line for the costs and the amount capitalized and expensed. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 14.F) -URI http://asc.fasb.org/extlink&oid=115993241&loc=d3e301413-122809 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5047-113901 + Details
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- Definition Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (d) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (e) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 + Details
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