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Property and Equipment - Schedule of Property and Equipment (Detail) - USD ($) $ in Thousands	Mar. 31, 2019	Dec. 31, 2018
Property, Plant and Equipment [Line Items]
Total property and equipment	$ 10,248	$ 10,427
Less: accumulated depreciation	(10,113)	(10,286)
Property and equipment, net	135	141
Office Equipment [Member]
Property, Plant and Equipment [Line Items]
Total property and equipment	233	266
Laboratory Equipment [Member]
Property, Plant and Equipment [Line Items]
Total property and equipment	4,536	4,561
Leasehold Improvements [Member]
Property, Plant and Equipment [Line Items]
Total property and equipment	5,383	5,504
Software [Member]
Property, Plant and Equipment [Line Items]
Total property and equipment	$ 96	$ 96

X

- Definition

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

+ References

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- Definition

Amount before accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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