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Commitments and Contingencies - Additional Information (Detail) - USD ($) $ in Thousands	1 Months Ended	3 Months Ended
	Jun. 30, 2012	Mar. 31, 2019	Mar. 31, 2018
Loss Contingencies [Line Items]
Rent expense under operating lease agreements		$ 400	$ 400
Operating Lease expense		400
Variable executory cost		300
Research and development expense		1,583	$ 3,286
Tissue Processor Sub License Agreement [Member]
Loss Contingencies [Line Items]
Research and development expense		700
Reimbursement for development cost	$ 300
Additional non-refundable royalty fee		$ 30
Additional non-refundable royalty fee payment description		2016 through 2019
Potential milestone payment		$ 10,200
Minimum [Member] | Tissue Processor Sub License Agreement [Member]
Loss Contingencies [Line Items]
Additional non-refundable royalty fee		20
Hydrogel License Agreement [Member]
Loss Contingencies [Line Items]
Research and development expense		3,200
Amount to be paid upon FDA approval		3,000
Tissue Regeneration License Agreement [Member]
Loss Contingencies [Line Items]
Research and development expense		800
Amount to be paid upon FDA approval		$ 300
Percentage of royalty offsetting		50.00%
Tissue Regeneration License Agreement [Member] | Minimum [Member]
Loss Contingencies [Line Items]
Non-refundable royalty fee		$ 10

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