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Consolidated Statements of Operations - USD ($)
shares in Thousands, $ in Thousands
 3 Months Ended
Mar. 31, 2019
Mar. 31, 2018
Income Statement [Abstract]    
Revenue $ 0 $ 0
Operating expenses:    
Research and development 1,583 3,286
General and administrative 2,929 2,807
Restructuring 2,789  
Loss on asset impairment 750  
Total operating expenses 8,051 6,093
Loss from operations (8,051) (6,093)
Other income (expense):    
Interest income, net 48 37
Other expense, net (5) (24)
Change in fair value of warrant liability (1,407) (8,753)
Total other income (expense), net (1,364) (8,740)
Net loss (9,415) (14,833)
Comprehensive loss (9,415) (14,833)
Net loss attributable to common stockholders-basic and diluted $ (9,394) $ (14,370)
Net loss per common share-basic and diluted $ (0.12) $ (0.52)
Weighted-average shares used to compute net loss per common share-basic and diluted 80,484,113 27,670,118