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Stock-Based Compensation - Summary of Stock-Based Compensation - Summary of Weighted-Average Assumptions Used in the Black-Scholes Option Pricing Model to Determine the Fair Value of the Employee Stock Option Grants (Detail)
3 Months Ended
Mar. 31, 2018
Employees [Member]  
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]  
Risk-free interest rate 2.70%
Expected volatility 88.20%
Expected term (in years) 6 years 29 days
Expected dividend yield 0.00%
Non Employees [Member]  
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]  
Risk-free interest rate 1.97%
Expected volatility 74.00%
Expected term (in years) 6 years 29 days
Expected dividend yield 0.00%