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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) | 9 Months Ended
--- | ---
Sep. 30, 2021 | Sep. 30, 2020
Cash flows from operating activities |  |
Net loss | $ (43,784,000) | $ (18,032,000)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation expense | 151,000 | 58,000
Non-cash interest expense | 59,000 | 555,000
Non-cash lease expense | 200,000 | 143,000
In-process research and development | 0 | 7,000,000
Stock-based compensation expense | 4,275,000 | 497,000
Income tax benefit | (52,000) | 0
Gain on forgiveness of PPP Note | (426,000) | 0
Impairment on note receivable | 761,000 | 0
Other non-cash | 0 | (166,000)
Changes in assets and liabilities: |  |
Prepaid expenses and other assets | 845,000 | 796,000
Accounts payable and accrued expenses | 2,925,000 | (1,133,000)
Other assets | 100,000 | 0
Lease obligations | (191,000) | (144,000)
Net cash used in operating activities | (35,137,000) | (10,426,000)
Cash flows from investing activities |  |
Purchase of property and equipment | (747,000) | (56,000)
Asset acquisition | (127,000) | 0
Issuance of note receivable | (750,000) | 0
Net cash used in investing activities | (1,624,000) | (56,000)
Cash flows from financing activities |  |
Proceeds from issuance of common stock | 128,606,000 | 26,693,000
Payment of equity issuance costs | (8,525,000) | (1,084,000)
Proceeds from issuance of debt | 0 | 921,000
Payments of debt issuance costs | 0 | (6,000)
Repayments of debt | 0 | (4,362,000)
Financing lease principal payments | (10,000) | (18,000)
Net cash provided by financing activities | 120,071,000 | 22,144,000
Net increase in cash, cash equivalents, and restricted cash | 83,310,000 | 11,662,000
Cash, cash equivalents, and restricted cash at beginning of period | 24,190,000 | 7,595,000
Cash, cash equivalents, and restricted cash at end of period | 107,500,000 | 19,257,000
Supplemental disclosure of non-cash investing and financing transactions: |  |
Exercise of warrants | 603,000 | 0
Series B Convertible Preferred Stock issuance | 4,988,000 | 0
Forgiveness of PPP Note | 426,000 | 0
Purchase of property and equipment | 9,000 | 0
Right-of-use asset related to operating leases | 926,000 | 0
Issuance of Warrant Exchange Promissory Notes | 0 | 5,625,000
Obligation settled with common stock | 0 | 331,000
Equity issuance costs | $ 0 | $ 25,000

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