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Loss per share (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Earnings per share [abstract]        
Net loss $ (50,608) $ (71,549) $ (131,643) $ (195,645)
Weighted average number of ordinary shares outstanding 78,372,680 76,739,770 77,374,388 76,730,117
Net loss per share, basic (in USD per share) $ (0.65) $ (0.93) $ (1.70) $ (2.55)
Net loss per share, diluted (in dollars per share) $ (0.65) $ (0.93) $ (1.70) $ (2.55)