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Operating expense - Schedule of Expenses by Nature (Details) - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended
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Sep. 30, 2023 | Sep. 30, 2022 | Sep. 30, 2023 | Sep. 30, 2022
Disclosure Of Detailed Information About Expenses By Nature [Line Items] |  |  |  |
Cost of product sales | $ 366 | $ 1,295 | $ 2,275 | $ 4,090
Research and development expense | 28,440 | 41,676 | 99,864 | 139,165
Sales and marketing expense | 13,730 | 16,847 | 43,537 | 52,876
General and administrative expense | 9,361 | 19,617 | 35,857 | 56,868
Operating expense | 51,897 | 79,435 | 181,533 | 252,999
External costs |  |  |  |
Disclosure Of Detailed Information About Expenses By Nature [Line Items] |  |  |  |
Research and development expense | 17,365 | 24,363 | 56,966 | 83,706
Sales and marketing expense | 8,035 | 8,236 | 23,724 | 26,406
General and administrative expense | 3,907 | 5,020 | 13,326 | 18,539
Employee expense |  |  |  |
Disclosure Of Detailed Information About Expenses By Nature [Line Items] |  |  |  |
Research and development expense | 11,075 | 17,313 | 42,898 | 55,459
Sales and marketing expense | 5,695 | 8,611 | 19,813 | 26,470
General and administrative expense | $ 5,454 | $ 14,597 | $ 22,531 | $ 38,329

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- Definition The amount of all expenses directly or indirectly attributed to the goods or services sold. Attributed expenses include, but are not limited to, costs previously included in the measurement of inventory that has now been sold, such as depreciation and maintenance of factory buildings and equipment used in the production process, unallocated production overheads, and abnormal amounts of production costs of inventories. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Name IAS -Number 1 -IssueDate 2023-01-01 -Paragraph 99 -URI https://taxonomy.ifrs.org/xifrs-link?type=IAS&num=1&code=ifrs-tx-2023-en-r&anchor=para_99&doctype=Standard -URIDate 2023-03-23 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Name IAS -Number 1 -IssueDate 2023-01-01 -Paragraph 103 -URI https://taxonomy.ifrs.org/xifrs-link?type=IAS&num=1&code=ifrs-tx-2023-en-r&anchor=para_103&doctype=Standard -URIDate 2023-03-23 + Details
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- Definition The amount of expense relating to general and administrative activities of the entity. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Name IAS -Number 1 -IssueDate 2023-01-01 -Paragraph 112 -Subparagraph c -URI https://taxonomy.ifrs.org/xifrs-link?type=IAS&num=1&code=ifrs-tx-2023-en-r&anchor=para_112_c&doctype=Standard -URIDate 2023-03-23 + Details
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- Definition The amount of expenditure directly attributable to research or development activities, recognised in profit or loss. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Name IAS -Number 38 -IssueDate 2023-01-01 -Paragraph 126 -URI https://taxonomy.ifrs.org/xifrs-link?type=IAS&num=38&code=ifrs-tx-2023-en-r&anchor=para_126&doctype=Standard -URIDate 2023-03-23 + Details
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- Definition The amount of expense relating to the marketing and selling of goods or services. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Name IAS -Number 1 -IssueDate 2023-01-01 -Paragraph 85 -URI https://taxonomy.ifrs.org/xifrs-link?type=IAS&num=1&code=ifrs-tx-2023-en-r&anchor=para_85&doctype=Standard -URIDate 2023-03-23 + Details
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