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Operating expense - Schedule of Expenses by Nature (Details) - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2023
Sep. 30, 2022
Sep. 30, 2023
Sep. 30, 2022
Disclosure Of Detailed Information About Expenses By Nature [Line Items]        
Cost of product sales $ 366 $ 1,295 $ 2,275 $ 4,090
Research and development expense 28,440 41,676 99,864 139,165
Sales and marketing expense 13,730 16,847 43,537 52,876
General and administrative expense 9,361 19,617 35,857 56,868
Operating expense 51,897 79,435 181,533 252,999
External costs        
Disclosure Of Detailed Information About Expenses By Nature [Line Items]        
Research and development expense 17,365 24,363 56,966 83,706
Sales and marketing expense 8,035 8,236 23,724 26,406
General and administrative expense 3,907 5,020 13,326 18,539
Employee expense        
Disclosure Of Detailed Information About Expenses By Nature [Line Items]        
Research and development expense 11,075 17,313 42,898 55,459
Sales and marketing expense 5,695 8,611 19,813 26,470
General and administrative expense $ 5,454 $ 14,597 $ 22,531 $ 38,329