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Property and equipment | 9 Months Ended
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Sep. 30, 2025
Property, Plant and Equipment [Abstract] |
Property and equipment | Property and equipment Property and equipment as of September 30, 2025 and December 31, 2024 consisted of the following:
(in thousands) |  | September 30, 2025 |  | December 31, 2024
Leasehold improvements |  | $ | 1,472 |  |  | $ | 3,873 |
Laboratory equipment |  | 2,949 |  |  | 4,415 |
Office equipment |  | 770 |  |  | 970 |
Hardware and computer software |  | 1,144 |  |  | 1,137 |
|  | 6,335 |  |  | 10,395 |
Less: accumulated depreciation |  | (6,335) |  |  | (5,320) |
Property and equipment, net |  | $ | — |  |  | $ | 5,075 |
Depreciation expense was nil and $705 for the three and nine months ended September 30, 2025, respectively, and $336 and $993 for the three and nine months ended September 30, 2024, respectively. In connection with the 2025 Restructuring, the Company recorded impairment of property and equipment of $5.0 million during the second quarter of 2025,related to leasehold improvements, lab equipment and furniture and fixtures located at the UK facility. See Note 15 for further information regarding the restructuring and associated impairment of long-lived assets. There were no impairments of property and equipment recorded during the three and nine months ended September 30, 2024.

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- Definition The entire disclosure for long-lived, physical asset used in normal conduct of business and not intended for resale. Includes, but is not limited to, work of art, historical treasure, and similar asset classified as collections. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 360 -Name Accounting Standards Codification -Publisher FASB -URI https://asc.fasb.org/360/tableOfContent Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Name Accounting Standards Codification -Section 50 -Paragraph 6 -SubTopic 360 -Topic 958 -Publisher FASB -URI https://asc.fasb.org/1943274/2147477798/958-360-50-6 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Name Accounting Standards Codification -Section 50 -Paragraph 1 -Subparagraph (d) -SubTopic 360 -Topic 958 -Publisher FASB -URI https://asc.fasb.org/1943274/2147477798/958-360-50-1 Reference 4: http://www.xbrl.org/2003/role/disclosureRef -Name Accounting Standards Codification -Section 50 -Paragraph 7 -SubTopic 360 -Topic 958 -Publisher FASB -URI https://asc.fasb.org/1943274/2147477798/958-360-50-7 + Details
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