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Accrued expenses and other current liabilities (Details) - USD ($) $ in Thousands | Sep. 30, 2025 | Dec. 31, 2024
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Organization, Consolidation and Presentation of Financial Statements [Abstract] |  |
Accrued R&D costs | $ 23,084 | $ 20,523
Accrued payroll and benefits | 8,818 | 13,600
Accrued restructuring costs | 3,598 | 0
Gross-to-net sales adjustments, short-term | 7,748 | 15,697
Operating lease liabilities, short-term | 933 | 1,371
Other | 9,744 | 11,249
Accrued expenses and other current liabilities | $ 53,925 | $ 62,440

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- Definition Carrying value as of the balance sheet date of obligations, excluding pension and other postretirement benefits, incurred through that date and payable for perquisites provided to employees pertaining to services received from them. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 210 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(20)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480566/210-10-S99-1 + Details
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- Definition Present value of lessee's discounted obligation for lease payments from operating lease, classified as current. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 842 -SubTopic 20 -Name Accounting Standards Codification -Section 45 -Paragraph 1 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org/1943274/2147479041/842-20-45-1 + Details
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