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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Sep. 30, 2025
Sep. 30, 2024
Revenue        
Product revenues, net $ 15,750 $ 18,016 $ 51,239 $ 52,894
License revenues and royalties 677 448 7,060 1,033
Total revenue, net 16,427 18,464 58,299 53,927
Operating expense        
Cost of product sales (1,202) (851) (4,099) (4,578)
Research and development (26,803) (32,502) (85,821) (82,532)
Selling and marketing (10,688) (10,673) (31,388) (32,764)
General and administrative (8,326) (10,002) (27,103) (32,271)
Restructuring and impairment expenses (377) 0 (13,468) 0
Total operating expense (47,396) (54,028) (161,879) (152,145)
Loss from operations (30,969) (35,564) (103,580) (98,218)
Other income (expense)        
Interest income 2,470 3,438 6,458 9,639
Interest expense (13,392) (13,117) (38,619) (38,292)
Other, net 925 1,624 946 1,783
Total other expense, net (9,997) (8,055) (31,215) (26,870)
Loss before income taxes (40,966) (43,619) (134,795) (125,088)
Income tax expense 0 (90) (1,419) (487)
Loss before equity in net losses of joint venture (40,966) (43,709) (136,214) (125,575)
Equity in net losses of joint venture 0 (260) 0 (1,544)
Net loss $ (40,966) $ (43,969) $ (136,214) $ (127,119)
Net loss per share        
Net loss per share, basic (in dollars per share) $ (0.30) $ (0.42) $ (1.14) $ (1.35)
Net loss per share, diluted (in dollars per share) $ (0.30) $ (0.42) $ (1.14) $ (1.35)
Weighted average shares outstanding, basic (in shares) 136,446,534 104,824,877 119,237,877 94,394,355
Weighted average shares outstanding, diluted (in shares) 136,446,534 104,824,877 119,237,877 94,394,355