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Segment reporting (Tables)

9 Months Ended

Sep. 30, 2025

Segment Reporting [Abstract]

Schedule of Segment Reporting Information, by Segment

The following table is the summary of the segment profit or loss information, including the significant expense categories for the three and nine months ended September 30, 2025 and 2024, respectively:

						Three Months Ended September 30,												Nine Months Ended September 30,
						2025						2024						2025						2024
Total revenues, net						$	16,427					$	18,464					$	58,299					$	53,927
Significant operating expenses:
Cost of product sales						(1,202)						(851)						(4,099)						(4,578)
Research and development(1)						(26,293)						(31,511)						(83,833)						(81,683)
Selling and marketing(1)						(10,345)						(10,318)						(30,422)						(32,852)
General and administrative(1)						(7,180)						(8,542)						(23,575)						(28,080)
Restructuring and impairment expenses						(377)						—						(13,468)						—
Share-based compensation						(1,999)						(2,806)						(6,482)						(4,952)
Total operating expenses						(47,396)						(54,028)						(161,879)						(152,145)
Loss from operations						(30,969)						(35,564)						(103,580)						(98,218)
Other segment items(2)						(9,997)						(8,405)						(32,634)						(28,901)
Net loss						$	(40,966)					$	(43,969)					$	(136,214)					$	(127,119)

(1)Excludes share-based compensation.

(2)Includes Other expense, net, Income tax expense and Equity in net losses of joint venture.

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- Definition

Tabular disclosure of the profit or loss and total assets for each reportable segment. An entity discloses certain information on each reportable segment if the amounts (a) are included in the measure of segment profit or loss reviewed by the chief operating decision maker or (b) are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 25
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482810/280-10-50-25

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 22
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482810/280-10-50-22

Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 30
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482810/280-10-50-30

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X

- References

No definition available.

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