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Accrued expenses and other current liabilities (Details) - USD ($) $ in Thousands	Sep. 30, 2025	Dec. 31, 2024
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Accrued R&D costs	$ 23,084	$ 20,523
Accrued payroll and benefits	8,818	13,600
Accrued restructuring costs	3,598	0
Gross-to-net sales adjustments, short-term	7,748	15,697
Operating lease liabilities, short-term	933	1,371
Other	9,744	11,249
Accrued expenses and other current liabilities	$ 53,925	$ 62,440

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Accrued Expenses And Other Current Liabilities

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Accrued Restructuring Costs, Current

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Carrying value as of the balance sheet date of obligations, excluding pension and other postretirement benefits, incurred through that date and payable for perquisites provided to employees pertaining to services received from them. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Topic 210
-SubTopic 10
-Name Accounting Standards Codification
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02(20))
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147480566/210-10-S99-1

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Present value of lessee's discounted obligation for lease payments from operating lease, classified as current.

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Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 842
-SubTopic 20
-Name Accounting Standards Codification
-Section 45
-Paragraph 1
-Subparagraph (b)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479041/842-20-45-1

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Amount of expenses incurred but not yet paid classified as other, due within one year or the normal operating cycle, if longer.

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-Topic 210
-SubTopic 10
-Name Accounting Standards Codification
-Section S99
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